Practice Exam Flashcards

1
Q

what effect does high sodium intake have on potassium secretion rate by kidneys?

A

has little effect

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2
Q

what would be the approximate volume of urine required to be excreted if all the excess H+ ions remained in free solution?

A

2700 L/day

if we weren’t able to buffer H+ ions and all had to be secreted

divide the numbers in the Q - 80/0.3 = 2700

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3
Q

which sensory endings in alveolar walls next to capillaries are sensitive to pulmonary edema?

A

J receptors

j = juxtaposition = means next to

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4
Q

what is the oxygen utilization coefficient at rest?

A

25%

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5
Q

what is the lowest pH that the normal kidneys can achieve ?

A

4.5

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6
Q
which factor decrease potassium uptake by cells?
aldosterone
metabolic acidosis
insulin
catecholamines
A

metabolic acidosis

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7
Q

H+ ATPase is first encountered in which part of renal tubule?

A

distal convoluted tubule

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8
Q

normally, how much H+ ions must be secreted each day in order to reabsorb 4320 mEq of filtered bicarbonate?

A

same number

4320 mEq of H+ ions

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9
Q

decreased concentrations of Ca ions in plasma would have direct effect on ?

A

increased release on PTH

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10
Q

normally, what is the transport maximum for glucose?

A

375 mg/min

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11
Q
which is a substance actively secreted into renal tubules?
urea
angiotensin II
creatinine
ADP
A

creatinine

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12
Q

which best describes capillary filtration coefficient?

  1. average diameters of glomerular capillaries
  2. mean of the capillary pressure w/in glomerulus
  3. product of permeability and filtering surface area of glomerular capillaries
A

product of permeability of filtering surface area of glomerular capillaries

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13
Q
which is a vasodilator that helps offset the effects of vasoconstrictors, especially on afferent arterioles?
bradykinin
endothelin
angiotensin II
norepinephrine
A

bradykinin

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14
Q
much of the oxygen consumed by the kidneys is related to ?
high rate of glucose
sodium 
potassium
amino acid reabsorption
A

active sodium reabsorption

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15
Q

which is responsible for partially inhibiting micturition except when it is desired?

A

pudendal nerves

other answers are related to ANS
but desired urination = voluntary aka somatic innervation

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16
Q

w/o autoregulation a slight increase in blood pressure increases GFR up to 225 L/day, how much would this increase urine flow?

A

46.5 L/day

normal = 180 GFR
normal urine flow = 1.5 L/day

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17
Q
what is the partial pressure of oxygen in mmHg at the alveolar membrane if the percentage in O2 in the alveoli is 20%?
75
122
152
266
A

152

find 20% of total atm pressure in alveoli

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18
Q

using the flick principle for calculating cardiac output, the patient’s resting O2 consumption volume should be divided by what ?

A

difference between systemic arterial and systemic mixed venous blood

19
Q

what is GFR if the urine conc. rate of substance is 125 mg/mL, flow rate is 2 mL/min, and plasma conc. of substance is 1 mg/mL?

A

250

renal clearance of inulin slide

20
Q

what mechanism is responsible for moving glucose?

A

secondary active transport via Na/glucose cotransporter

21
Q

what accounts for heart rate increase upon transitioning from lying to standing up?

A

decreased venous return

22
Q

what is a factor resulting in hypokalemia?

A

excess secretion of aldosterone

23
Q

an increase in what will result in a decrease in glomerular hydrostatic pressure?
arterial pressure
afferent arteriolar resistance
efferent arteriolar resistance

A

afferent resistance

24
Q
what center acts to control the off switch point of the inspiratory ramp signal?
DRG
VRG
Pneumotaxic center
aortic body
A

Pneumotaxic center

25
``` ADH is formed in supraoptic and paraventricular nuclei, secreted by special neurons from where? adrenal cortex adrenal medulla ant. pituitary post. pituitary ```
post. pituitary
26
``` max urine conc. is 1200 mOsm/L, what represents the obligatory urine volume that must be excreted each day to get rid of metabolic waste products? 1 0.5 0.3 0 ```
0.5 L/day
27
ADH acts on which of the following regions of the nephron?
distal convoluted tubule
28
``` which of the following reflects the amount of urine that the kidneys can excrete per day when there is a large excess of water? 180 75 20 4 Liters ```
20 L
29
which of the following reflects the max urine conc. that can be produced by the kidneys?
1200 - 1400
30
because of paracellular diffusion of ions back into the tubule, what is the upper limit of conc. gradient created by countercurrent mechanism?
200 at the top of the loop of henle going into distal countercurrent mechanism slide
31
osmoreceptor cells are located where?
anterior part of the third ventricle
32
which would not shift the O2-Hb curve right and down?
delta
33
what percentage of CO2 is carried in blood as bicarbonate?
70%
34
which respiratory control center is primarily responsible for establishing the ramp signal during normal breathing?
DRG
35
what is the source of aldosterone?
adrenal cortex
36
Mg and Ca are reabsorbed from tubular lumen thru which mechanism?
paracellular transport due to positive charge in tubular lumen
37
shrinkage of osmoreceptor cells...…..leading to release of what?
ADH
38
chemoreceptor response to hypoxia or hypercapnia is to increase function. T/F?
TRUE
39
most filtered electrolytes are reabsorbed in which part of kidney tubule?
proximal convoluted tubule
40
the lower pH of tubular fluid brings operating range of the buffer closer to pK of which system?
bravo
41
which of the following would not be true regarding the Haldane effect?
O2-Hb dissociation curve shifts right
42
what must happen before filtered bicarbonate can be reabsorbed?
delta | must react w/ H+ to form carbonic acid
43
which segment of nephron is not permeable to water?
ascending loop of henle in presence of ADH