Practice Qs

Question 1

What can lithium treatment cause?

Answer 1

Diabetes insipidus

Question 2

How is desmopressin administered?

Answer 2

Nasal spray for treatment and subcutaneous route is used only for DI testing

Question 3

What can thyroxine be synthesised from?

Answer 3

Tyrosine

Question 4

Can cushing’s disease be associated with hyperpigmentation?

Answer 4

Yes

Question 5

What will urinary cortisol levels be for someone with conn’s syndrome?

Answer 5

High

Question 6

What is northisterone?

Answer 6

A progestogen and derivative of testosterone, it is not an oestrogen

Question 7

What can menopause be confirmed by?

Answer 7

Raised levels of LH in circulation

Question 8

What is HRT associated with? - begins with a c

Answer 8

cholecystitis

Question 9

What kind of environment does fertilisation require?

Answer 9

Progesterone- stimulated calcium influx into sperm

Question 10

What hormones does decidualisation need?

Answer 10

Progestogen and oestrogen

Question 11

Do you use ketoconazole and metyrapone in con’s syndrome?

Answer 11

no- reduces the amount of cortisol which we don’t want

Question 12

What is phenyloxabenzamine?

Answer 12

Alpha blocker, can be used in phaeo

Question 13

What does metformin do?

Answer 13

Sensitises cells to insulin (?)

Question 14

Which 5 hormones increase plasma glucose levels?

Answer 14

Glucagon, cortisol, growth hormone, thyroxine, adrenaline

Question 15

What are the effects of insulin on fatty acid oxidation in muscle?

Answer 15

Insulin inhibits fatty aid oxidation in muscle

Question 16

Name 3 diseases resulting in low vitamin D

Answer 16

liver failure, kidney failure, malabsorption in the gut (crohn’s, ulcerative colitis)

Question 17

What does the glucose tolerance test show when a person has growth hormone excess and when normal?

Answer 17

GH excess- growth hormone will remain high and not decrease, blood glucose will increase and cause insulin resistance and diabetes
Normal- growth hormone decreases when glucose is administered

Question 18

Apart from D2 agonists and somatostatin analogues, what are other treatments for growth hormone excess?

Answer 18

Surgery, radio/chemotherapy

Question 19

What affect does vasopressin have on corticotrophin?

Answer 19

VP increases corticotrophin release

Question 20

What is terlipressin used in?

Answer 20

Targets V1 receptors and is used in oesophageal varices

Question 21

What happens to total potassium levels in the body and in the plasma?

Answer 21

Total body K+ deficiency alongside a raised plasma K+ concentration