Practice Qs Flashcards
(21 cards)
What can lithium treatment cause?
Diabetes insipidus
How is desmopressin administered?
Nasal spray for treatment and subcutaneous route is used only for DI testing
What can thyroxine be synthesised from?
Tyrosine
Can cushing’s disease be associated with hyperpigmentation?
Yes
What will urinary cortisol levels be for someone with conn’s syndrome?
High
What is northisterone?
A progestogen and derivative of testosterone, it is not an oestrogen
What can menopause be confirmed by?
Raised levels of LH in circulation
What is HRT associated with? - begins with a c
cholecystitis
What kind of environment does fertilisation require?
Progesterone- stimulated calcium influx into sperm
What hormones does decidualisation need?
Progestogen and oestrogen
Do you use ketoconazole and metyrapone in con’s syndrome?
no- reduces the amount of cortisol which we don’t want
What is phenyloxabenzamine?
Alpha blocker, can be used in phaeo
What does metformin do?
Sensitises cells to insulin (?)
Which 5 hormones increase plasma glucose levels?
Glucagon, cortisol, growth hormone, thyroxine, adrenaline
What are the effects of insulin on fatty acid oxidation in muscle?
Insulin inhibits fatty aid oxidation in muscle
Name 3 diseases resulting in low vitamin D
liver failure, kidney failure, malabsorption in the gut (crohn’s, ulcerative colitis)
What does the glucose tolerance test show when a person has growth hormone excess and when normal?
GH excess- growth hormone will remain high and not decrease, blood glucose will increase and cause insulin resistance and diabetes
Normal- growth hormone decreases when glucose is administered
Apart from D2 agonists and somatostatin analogues, what are other treatments for growth hormone excess?
Surgery, radio/chemotherapy
What affect does vasopressin have on corticotrophin?
VP increases corticotrophin release
What is terlipressin used in?
Targets V1 receptors and is used in oesophageal varices
What happens to total potassium levels in the body and in the plasma?
Total body K+ deficiency alongside a raised plasma K+ concentration
