practicum 50 multiple choice Flashcards

1
Q

Abs that can cause a HDN

A

ABO/Rh, Kell, Duffy

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2
Q

Abs that may cause HTR

A

Kidd, ABO incompat.

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3
Q

Abs that may cause Delayed HTR

A

Kidd (jka, jkb), Duffy, Kell, MNS

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4
Q

How are cold agglutinans excluded from testing?

A

cold agglut-absorption

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5
Q

How is rouleaux excluded from testing?

A

saline replacement

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6
Q

What Abs are detected at IS?

A

Lewis, MN, P1

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7
Q

What Abs are detected at 37 degrees?

A

Rh, MN

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8
Q

What Abs are detected at AHG phase?

A

Kell, Duffy and Kidd

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9
Q

Interval between donations

A

8 weeks

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10
Q

minimum Hgb for donation

A

> 12.5

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11
Q

minimum Hct for donation

A

> 38%

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12
Q

maximum volume of blood drawn during donation

A

525 mL (normal 450 mL)

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13
Q

minimum body weight for donation

A

110 lbs

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14
Q

max body temp for donation

A

37.5/ 99.5

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15
Q

how long is the deferred period if person spent time in a malaria area?

A

1 year

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16
Q

how long is the deferral after having malaria?

A

3 years

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17
Q

what blood type is used for emergency release and alternate blood selection?

A

O pos

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18
Q

Refrigerator temp for RBCs

A

1-4 degrees

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19
Q

shelf life after breakage of hermetic seal

A

24 hrs

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20
Q

length of time recipient samples are saved for

21
Q

temp range during whole blood shipping

22
Q

reason to discard a unit of blood

A

hemolyzed

clots

23
Q

which blood group has the most reactivity with anti-H

A

Group O is strongest

24
Q

hemophiliac patient would need what type of blood component?

A

cryo (contains concentrated fibrinogen and factor VIII)

25
what is unique about the Lewis system
only blood group system not manufactured by the RBCs. pregnant women may present Le(a-b-) and produce Lewis Abs even though true phenotype is Le(a-b+). can show in saliva and tears
26
what Abs are found in Bombay individuals?
ALL | Anti-A, Anti-B, Anti-A,B, H
27
what blood group Ags are enhanced by enzymes?
Lewis, Rh, Kidd
28
what blood group Ags are destroyed by enzymes?
Duffy, MNS
29
what would you expect if a Rh neg patient who has never been transfused or pregnant was transfused with pos donor blood?
no transfusion reaction because no Abs are present due to no previous exposure
30
when should Rhogam be given
Rh - mother Rh+ baby
31
define elution
used to remove Abs that may be bound to the RBCs
32
define forward typing
using forward known serum Abs to detect unknown Ags
33
define DAT
used to diagnose HDN, HTR and AIHA if + perform an elution to remove Ab to ID specific eluate (( Direct Coombs use patient cells))
34
define polyspecific
has both complement and IgG
35
what is the anti-A1 lectin used to detect
used with A1-ABO discrepancy
36
where do you find whartons jelly
on cord blood cells
37
why aren't reverse blood groupings done on newborns
no developed Abs
38
define febrile nonhemolytic reaction
chills, fever, increase in temp by 2 degrees
39
what could a weak supgroup of A cause
ABO discrepancy
40
what would you use distinguish between an A1/A2 discrepancy?
dolichus Biflorus
41
if the mother is O and the baby is A and there is HDN what would you transfuse with?
Group O blood
42
what would be the next step if cord blood and mother sample have a strong + DAT?
elution
43
would A2B and anti-A1 cause a discrepancy?
yes
44
why are cells washed in the AHG test?
to prevent neutralization by globulins
45
what is the reason for a mixed field result on a DAT for a patient who has been previously transfused
2 cell population in the patients blood
46
what type of sample do you need for compatibility testing?
fresh serum/plasma
47
why do you need a fresh serum sample for compatibilty
to preserve complement
48
what type of elution is required for HDN
Acid Elution
49
what is a cause for deferral during blood donation
if they tested positive for HBsAg