PRBC transfusion Flashcards
(3 cards)
1
Q
Risks-
TRALI
TRIM
TACO
A
Transfusion reactions- extremely rare- mostly due to clerical error
Even rarer in exsanguinating pts- likely due to alterations in immune system caused by the injury needing massive transfusion.
2
Q
TRALI
A
Noncardiogenic pulmonary oedema that occurs within 4-6hrs post transfusion
More of a localised pulmonary inflammation
Most common following Plasma transfusion.
3
Q
TRIM
A
TRALI and TRIM likely variants of same disorder-
Exaggerated inflammatory response and damaged immune system.
Represents systemic immune derangement
Mech:
Cotransfusion of soluble proteins eg- FDPs, HLA, disrupted WBCs all implicated.
Best exemplified by reports showing increased incidence of infection follow transfusion of PRBC
