Pre-op 1/21 Flashcards

Test 1 (50 cards)

1
Q

What is the most common NMB allergy?

A

Rocuronium

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2
Q

What would be a way that you can tell that a patient is having an allergic reaction while under anesthesia?

A

Cant ventilate them

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3
Q

What are factors that increase your risk of latex allergy?

A

Multiple Sx
-occupation: healthcare workers; food handlers
-food allergies: mangoes; kiwi; avocado; passion fruit; banana; chestnut
-spina bifida

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4
Q

What adverse effects can local anesthetics cause?

A

Increased HR dt epi

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5
Q

Which local anesthetics have a lower risk of allergic reactions? Why?

A

Amides have a lower risk for allergic reactions than esters

Esters have a perservative para-aminobenzoic (PABA)

Amides: Lidocaine, Bupivcaine,

Esters: Procaine, chloroprocaine,

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6
Q

What allergies have cross activity with NMB?

A

Morphine
Neostigmine

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7
Q

What BP medication do we need to d/c at least 24 hrs prior to Sx? Why?

A

ACE inhibitors

Makes BP hard to manage

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8
Q

What consideration should we have for all contraceptives?

A

High risk pt for postop venous thrombosis should DC four weeks prior to Sx

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9
Q

If patient is already taking a opioid, what considerations should i have?

A

I can give opioid that works on different opioid receptors

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10
Q

What consideration should we have with patient taking aspirin prior to surgery?

A

Cont if significant CVS disease/event

if not, d/c 10-14 days prior to surgery

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11
Q

What consideration should we have with Cox-2 inhibitors?

A

They can affect bone healing, can DC prior to surgery

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12
Q

what consideration should we have with MAOIs medication’s?

A

Avoid meperidine and indirect acting vasopressors (ephedrine)

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13
Q

What consideration should we have with P2Y12 inhibitors? (Antiplatelets)

A

Do not d/c with stent for Sx until 6 months of dual therapy

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14
Q

What are the d/c time frames for P2Y12 inhibitors? (Antiplatelets)

A

Clopidogrel/ticagrelor: 5-7 days
-Prasugrel: 7-10 days
-Ticlopidine: 10 days

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15
Q

When should topical & diuretics medications be d/c? What is the exception?

A

The day of Sx

Continue Thiazide diuretics

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16
Q

Sildenafil is ______ and should be d/c ____ before Sx

A

viagra

24

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17
Q

What are all the medications you d/c before Sx?

A

ASA
P2Y inhibitors (clopidogrel)
Topicals
Diuretics (not thiazides)
Sildenafil
NSAIDS
Warfarin
Postmenopausal Hormone Replacement Therapy (HRT)
Non-insulin anti-diabetic medication’s

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18
Q

When do we d/c NSAIDs before Sx?

A

48 hours

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19
Q

When do we d/c warfarin before Sx?

A

5 days

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20
Q

When do we d/c Post menopausal HRT before Sx?

A

4 weeks

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21
Q

When do we d/c non-insulin anti-diabetic medication before Sx?

22
Q

When do we d/c SGLT inhibitors before Sx?

23
Q

What is the protocol for insulin the day of Sx for type 1 vs type 2?

A

Type 1: 1/3 or normal dose of long acting insulin in the morning

Type 2: none or up to 1/2 of normal dose of long acting insulin in the morning

24
Q

What are the periop corticosteroid doses?

A

50 mg IV before incision

25 mgs q8h for 24 hours

Theres more but this should be all im worried about

25
OTC herbal considerations: Echinacea
Activation of cell mediated immunity: Allergic reactions -immunosuppression
26
OTC herbal considerations: ephedra
**d/c 24h before Sx** Increases HR and BP through sympathomimetics: -increase risk for CVS event -ventricular arrhythmias with halothane -hemodynamic instability -interacts with MAOIs
27
OTC herbal considerations: garlic
**d/c 7 days before Sx** -inhibits platelet aggregation -antihypertensive activity
28
OTC herbal considerations: ginger
-antiplatelet -antiemetic
29
OTC herbal considerations: Ginkgo
**d/c 36h before Sx** -inhibits platelet activating factor
30
OTC herbal considerations: Ginseng
**d/c 7 days before Sx** -inhibits platelet aggregation -lowers blood glucose -Decreases anticoagulant effect of warfarin
31
OTC herbal considerations: Green tea
**d/c 7 days before Sx** -inhibits platelet aggregation
32
OTC herbal considerations: Kava
**d/c 24h before Sx** -sedation/axiolysis
33
OTC herbal considerations: Saw Palmetto
-inhibits Cox: increase risk of bleeding
34
OTC herbal considerations: St. John's wort
**d/c 5 days before Sx** -inhibits neurotransmitter reuptake -decreases serum digoxin levels -delayed emergence -**interacts with a lot of things**
35
OTC herbal considerations: valerian
-sedation -may increase aesthetic requirements with long-term use -may increase sedative effects
36
What are the NPO status guidelines?
Full meals: 8 hours Light meals: 6 hours Breast milk: 4 hours Clear liquids: 2 hours
37
Can I give PO meds with NPO status?
Yes. Unless actively N/V, yes.
38
What is Mendelson syndrome? What does it indicate?
Gastric residual >25cc -gastric pH <2.5 Increase risk of aspiration & increases mortality greatly
39
How can we decrease the risk of aspiration?
**Decrease gastric volume or increase gastric pH** -antacids (sodium citrate) -H2 receptor antagonist (famotidine, ranitidine, cimetidine) -PPI (omeprazole, pantoprazole) -dopamine two antagonist (metacloperamide-psychotic effects)
40
T/F: smoking decreases your risk of having N/V
T
41
What sedation helps with vomiting?
Propofol
42
What medications help with N/V?
Scopolamine: acetylcholine muscarinic antagonist -apply night before Sx **-worsens narrow angle glaucoma** Pregabalin: GABA analogue -reduces opioid requirements -administer pre-induction Ondansetron: serotonin antagonist -administer before conclusion of surgery -prolonged QTc Promethazine: H1 antagonist -causes sedation Dexamethasone: steroid -administer after induction -may release endorphins or inhibit prostaglandin synthesis **most of these cause blurry vision, dry mouth, HA, visual disturbances**
43
All patients should have received prophylactic antibiotics within ______ before surgical incision
1 hour
44
Which antibiotics allow to be given within 2 hours of surgical incision?
Vancomycin Fluoroquinolone
45
What are the common Abx given for Sx? Which is the most common? What are the main differences in them?
Cefazolin: **Most common** -Broad spectrum Beta-lactam - PCN cross reactivity Clindamycin: gram pos > neg -alt for beta-lactam allergy or MRSA Vancomycin: Gram positive -alt for beta-lactam or MRSA
46
What Sx would we use Vancomycin for?
distal ilium -colon -appendix
47
What Sx/infections would we use Clindamycin for?
infections: head/neck -respiratory tract -bone -soft tissue -abdomen -pelvis Sx: hysterectomy -appendectomy -gastroduodenal tract -biliary tract -small intestine -colon -rectum
48
What is my dosing for Cefazolin?
Adult: 2g -3g if >120 kg Pediatric: 30 mg/kg **give over 30 minutes**
49
What is my dosing for Clindamycin?
Adult: 900 mg Pediatric: 10 mg/kg **give 30-60 mins**
50
What is my dosing for Vancomycin?
Adult: 15mg/kg Pediatric: 15mg/kg **Give 15mg/min**