Pregnancy Flashcards
(15 cards)
What is IVF?
A form of assisted reproductive technology where an egg is fertilised by sperm outside the body
What are the 8 steps to IVF?
- Controlled ovarian hyperstimulation
- Oocyte pick up
- Sperm collection and prep
- Insemination
- Fertilisation and embryo development
- Embryo selection
- Embryo transfer
- Embryo cryopreservation
How many babies are born via fertility treatment in Australia?
1 in every 18
When should a couple seek fertility help under 35 years old?
Trying for 12 months or longer
When should a couple seek fertility help over 35 years old?
Trying for 6 months or longer
When are eggs collected in IVF?
On day 0 following an ovulation trigger
What are the two types of insemination in IVF?
- IVF
- ICSI
What is the difference between IVF and ICSI?
- IVF: oocytes mixed with sperm
- ICSI: single sperm injected into each oocyte
What are four pros of IVF?
- Higher live brith rate than ICSI
- Lower congenital abnormality rate
- More nature, cheaper and faster
- Less operator dependent
What are three cons of IVF?
- Cannot use frozen oocytes or surgical sperm
- Not suitable with poor sperm quality
- Risk of fertilisation failure around 5%
What are five pros of ICSI?
- Works with poor sperm/frozen oocytes
- Guarantees 1 sperm per mature egg
- Reduced contamination
- Allows time lapse incubation
- Preferred by some patients
What are five cons of ICSI?
- Lower live brith rate
- Higher congenital abnormality rate
- Expensive and time consuming
- More stress on oocytes
- Operator dependent
What media do sperm and oocytes need?
- Sperm need fructose or glucose
- Oocytes need lactate and pyruvate not glucose
- EDTA to prevent 2-cell block
What are the three ways embryos are assessed?
- Morphology
- Morphokinetics
- Preimplantation genetic testing
What are the two cryopreservation options and when are they used?
- Slow freezing on day 1 embryos
- Vitrification on day 5 embryos