PRELIM Flashcards

1
Q

Branch of medicine and medical imaging that uses a small amount of what we call radio tracers, or radiopharmaceuticals, to diagnose disease and to treat disease, including many types of cancers, heart diseases and certain other abnormalities within the body.​

A

NUCLEAR MEDICINE

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2
Q

Nuclear medicine looks at ________ of the body and of all the organ systems. We can follow the physiological processes as they occur in a living human using these radiopharmaceutical and through use of appropriate imaging system.​

A

physiology

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3
Q

Martin Klaproth discovers Uranium and named it after the planet Uranius​

A

1979

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4
Q

Henri Becquerel uses Uranium and radium to discover alpha and beta rays, type of radiation​

A

1896

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5
Q

who discovered gamma rays

A

Paul Villard

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6
Q

Pierre and Marie Curie first used the word “radiation” to describe the rays they were finding; they also discovered Polonium and radium.​

A

1989

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7
Q

used radiation to kill bacteria in food​ & what year

A

Samuel Prescott, 1989

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8
Q

Ernest Rutherford and Frederick Soddy establishes the theory of Nuclear Reactions (by bombarding alpha and beta particles)​

A

1902- 1919

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9
Q

Father of Nuclear Medicine, conceives the idea of radioactive tracers​

A

1911 – George von Hevesy

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10
Q

a Boston physician, first used radioactive tracers to diagnose heart diseases.​

A

1927 – Herman Blumgart

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11
Q

discovery of artificial radioactivity

A

Frederic Joliot-Curie and Irene Joliot-Curie​; 1934

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12
Q

discovery of Fe-59

A

John Livingwood, Fred Fairbrother, Glenn Seaborge; 1937

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13
Q

an artificial element to fill space number 43 in the periodic table​

A

Technetium 99

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14
Q

Technitium 99m discovered by

A

C. Perrier and E. Segre; 1937

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15
Q

The building block of a radiographer’s understanding of interactions between ionizing radiation and matter​

A

atom

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16
Q

Came from the Greek word, “atomos” which means _______

A

indivisible​

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17
Q

Smallest part of an element that has all the properties of that element.​

A

atom

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18
Q

The basic component and the smallest unit of matter​

A

atom

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19
Q

it is neutrally charged because the number of protons is equal to the number of electrons​

A

atom

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20
Q

Central core of an atom​

A

nucleus

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21
Q

Contains nearly all the mass of an atom​

A

nucleus

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22
Q

Positively charged​

Contains the nucleons (protons+neutrons)​

A

nucleus

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23
Q

Composed of electrons, which is negatively charged.​

A

Orbits / Shells​

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24
Q

Positively Charged and has an atomic mass of 1​

A

Proton

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25
no charge or Neutrally charged and has an atomic mass of 1​
neutron
26
negatively charged and the lightest among the subatomic particles​
electron
27
atomic mass of 1/1836 or approximately________
1/2000​
28
the smallest chemical unit of an element or compound that exist independently​
molecule
29
what year: discovery of radioactivity
1896
30
The property of certain nuclides to spontaneously emit radiation in form of alpha, beta, and gamma rays and other nuclear fragments to reach a stable state.​
radioactivity
31
who discovered radioactivity
Antoine Henri Becquerel​
32
SI unit of radioactivity
becquerel (Bq)​
33
1 Bq =
1 dis/s (disintegration per second or dps)​
34
old unit for radioactivity
curie (Ci)
35
coined the term radioactivity and also discovered Polonium and Radium, with the helped of her husband, Pierre Curie​
Marie Curie
36
unstable of emitting radiation spontaneously to reach a more stable state; termed also as radioactive materials​
Radioactive Atoms
37
A fraction or percentage of original number of atoms decaying per unit time​
Decay Disintegration / Transformation Constant​
38
The amount of time taken by the radioactive material (RAM) or radioactive atom to decay to ½ of its original value​ Every RAM has its own unique half life value​
half-life
39
half-life of Tc-99
6hrs
40
half-life of I-131
8 days
41
half-life of I-123
13 hrs
42
half-life of Ra-223
11 days
43
half-life of Ra-226
1620 yrs
44
half-life of Co-60
5.26 yrs
45
half-life of Cs-137
30 yrs
46
half-life of Ir-192
74 days
47
half-life of Sr-90
28 yrs
48
half-life of Mo-99
66 hrs
49
the process wherein the unstable atom (parent) spontaneously emits radiation to reach a more stable state (daughter)​
Radioactive decay
50
is unstable atom or radioactive atom​
parent
51
is a new atom that is already a stable state​
daughter
52
Occurs in heavy nuclides with high atomic number​
Alpha Emission/Decay (α-decay)​
53
It resembles the Helium (He) element​
Alpha Emission/Decay (α-decay)​
54
relative charge of alpha is ___ and a mass of _____
2, 4
55
has low penetrating power and most harmful internally and less harmful externally.​ it can be stopped by a piece of paper or cloth.​
alpha radiation
56
The relative charge of -1 and a mass of 0.​
Beta Decay/ Emission
57
has a moderate energy and it can be stopped by approximately 0.5mm aluminum or lead.​
Beta Decay/ Emission
58
This occurs when there are too many neutrons.​ It occurs when a radioactive nuclide with high Neutron and Proton ratio disintegration​ This particle emitted is a negatively charge high speed electron which originated in the nucleus.​ This electrons results from the conversion of the excess neutron into proton.​
negatron emission
59
It occurs when the radioactive nuclide with an excess of Proton disintegrates​ The particle emitted is positively charged electron which comes from the nucleus​ This results from the transformation of the excess proton to a neutron​ With Positron emitter, the parent nucleus gives up positive charge resulting in a daughter less positive by one unit of charge.​ The atomic number decrease by one and the mass number remains unchanged.​
Positron Emission or Beta Positive emission
60
Excited state element​ Radionuclide that yields another nuclide during disintegration​ Long-lived radionuclide​
parent nuclide
61
Ground state element​ Element that results from the radioactive decay of a parent element.​ Short-lived radionuclide​ ​
daughter nuclide
62
Have high penetrating power and it can be stopped by several centimeters of lead.
gamma rays and x-rays
63
originates from the nucleus​
gamma ray
64
originates from the electrons​
x-ray
65
originate from the nucleus​
beta particles
66
originate from the e- clouds.​
electrons
67
is the nuclear medicine laboratory technique for measuring trace amount of substances in the blood. (substances being measured with RIA are the least 1000 times less)
Radioimmunoassay (RIA)
68
- for brain, liver, lung, bone, kidney, heart, thyroid, and other organs for detection of a tumor. Whole body imaging for the detection of metastases.
Imaging studies
69
are thyroid uptake to determine thyroid function, renography for the investigation renal function, and blood volume measurement.
Non-imaging studies
70
It uses a small amount of radioactive material
unsealed source
71
means “open”
“Unsealed”
72
it evaluates the function of the organ
Nuclear Medicine
73
Two Classes of Nuclear Medicine Imaging
Single Photon Imaging Positron Imaging
74
2 General Components of radiopharmaceutical
Radionuclide Pharmaceutical
75
Are medicinal products designed for the use in the investigation or treatment of human diseases.
Radiopharmaceuticals
76
Contain “radionuclide” as an integral part of the main ingredient.
Radiopharmaceuticals
77
Are administered to a human subjects usually by intravenous injection.
Radiopharmaceuticals
78
-The atoms involved and the only nuclei that undergo radioactive decay -Emits gamma ray as it decays This is tagged to a radiopharmaceutical
Radionuclide
79
-Any chemical substances intended for use in medical diagnosis, cure treatment or prevention of disease. -Carries the radionuclide to the organ being examined. -This is chosen in the basis of its preferential localization or participation in the physiological function of a given organ. -Produces gamma-ray emission from within the organ is being studied.
Pharmaceuticals/Tracer