prelim 2 part 2 Flashcards
(57 cards)
what makes up extracellular fluid
water, electrolytes- dissociate in ions (salts, acids, bases, some proteins) and non electrolytes- organic molecules that dont dissociate and have no electrical charge
extracellular fluid major cation and anion
cation- sodium
anion- chloride
what are extracellular fluids for
maintain cell structure
ensure cell function
vehicle for nutrients and chemical s
how does ECF maintain cell structure
- water alters the volume of cells (remember osmosis and red blood cells)
- hydrostatic pressure maintains tissues and organs in place
how does ECF ensure cell function
Ions are required for cell function (ex: enzymes)
- Maintain electrical gradients across membranes (allowing action potentials)
conformers
don’t regulate- osmotic pressure is exactly proportional to ECF (environmental controls line)
ECF varies greatly
no homeostasis- cells are isoosmotic with environment
regulators
regulate, keep osmolarity constant
use homeostasis
energetically costs
What parameters can organisms regulate?
VOLUME of water in the ECF volume regulation
CONCENTRATION of ions available in the ECF
ionic regulation
OSMOTIC PRESSURE (concentration) of the ECF
osmotic regulation
conformers environments
no homeostasis so typically stable environments, marine
regulators environments
unstable,
inhospitable habitats- salty or terrestrial
fish in fresh water problems
diluted solutionSalt in ECF gets lost by diffusion and osmosis makes water goes in
Need to prevent loss of salt and gain of water
fish in fresh water solution
Gills actively uptake Na+ (salt) and cL- (separately actively pumped into animal, both pumps use ATP, also cotransport a waste ion to maintain )
Excretion of large amounts of water in dilute urine from kidneys
fish in sea water problem
Facing desiccation and inward salt diffusion
Water in body go out, salt go in
fish in sea water solution
Gills actively secrete Cl- and Na+ follows actively/passively
Excretion of salt ions and small amounts of water in scanty urine from kidneys
review of fresh water challenges and solution
low osmolarity environment water comes in by osmosis ions diffuse out dilution risk solution: diluted urine, gills uptake Na+ and Cl-
review of sea water challenges and solutions
high osmolarity environment water goes out by osmosis ions diffuse in concentration risk solution: concentrated urine gills secrete cl-, and Na+ follows
isotonic dehydration
n (loss of fluid, without changing concentration).
is also called Hypovolemia: decrease in volume of blood plasma. not enough ECF
hypertonic dehydration
with high electrolyte levels (often hypernatremic dehydration). True dehydration, too much sakt, enough fluid but bad concentration
regulation of water and salt intake
thirst
regulation of salt and water output
excretion
trigger true dehydration and response
Electrolyte concentration in ECF increases
Increase osmolarity
Osmoreceptors sense osmolarity of ECF, see ECF is too concentration, they activate intracellular thirst
Stress on cell
Drink water
trigger hypovolemia and response
Fluid volume is decreased, Decrease in plasma volume Baroreceptors sense decrease in pressure Trigger thirst extracellular (less volume in circulation) Drink water and eat salt
Osmoreceptor cells and intracellular thirst, respond to what change and how
Osmoreceptor cells are sensitive to ECF osmolarity to the 1-2% increase in osmolarity
They alter their electrical activity (action potentials) in response to increase in ECF osmolarity
Cell shrinkage due to osmosis is the signal detected by these neurons
how salty foods correlate to hypertension
Eat a lot of salt- dehydrated therefore drink more water
Plasma will have high osmotic pressure
Kidney will decrease its function to retain water
Water will flow into interstitial pressure (oedema)
Increase volume of ECF
increase blood pressure
Increase in blood pressure could aggravate hypertension