Pressure and Flow in Arteries and Veins Flashcards

(41 cards)

1
Q

How is arterial pressure measured

A

Auscultation of Korotkoff sounds using sphygmomanometer and stethoscope

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2
Q

Systolic pressure sound

A

Tapping

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3
Q

Diastolic pressure sound

A

Silence

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4
Q

Order of pressure sounds from high cuff pressure to lower

A

Silence, tapping, thumping, muffled, silence

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5
Q

Disadvantages of measuring by Korotkoff sounds

A

Low accuracy
Discontinuous
Needs care

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6
Q

Advantages of measuring by Korotkoff sounds

A

Non-invasive

Cheap

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7
Q

Energy changes in aorta during systole and diastole

A

Absorb energy during systole and release energy during diastole

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8
Q

Elastic arteries act as

A

Pressure reservoir

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9
Q

Pressure wave of arteries is affected by

A

Stroke volume and velocity of ejection - rising phase
Elasticity of arteries - both
Total peripheral resistance - falling phase

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10
Q

Normal arterial pressure

A

120/80mmHg

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11
Q

Effect of age on arterial pressure

A

Increases

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12
Q

Pressure from arteries to veins

A

Decreases

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13
Q

Pressure drop in arteries

A

Small = 95 to 90 mmHg

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14
Q

Pressure drop in arterioles

A

Large = 90 to 40 mmHg

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15
Q

Pressure drop in veins

A

Small = 20 to 5 mmHg

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16
Q

Velocity is related to

A

Total cross section

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17
Q

Velocity is greatest in

A

Aorta and vena cava

18
Q

Velocity is lowest in

19
Q

Veins are

A

Distensible and collapsible

20
Q

External influences that affect flow in veins

A
Gravity
Skeletal muscle pump
Respiratory pump
Venomotor tone
Systemic filling pressure (main)
21
Q

Pressure in body due to gravity

A

Low pressure at head and high pressure at feet

22
Q

Gravity does not affect

A

Pressure from arteries to veins

23
Q

Gravity causes

A

Venous distension in legs and neck

24
Q

Effects of venous distension in legs

A

Decrease EDV, preload, stroke volume, cardiac output and main arterial pressure
Orthostatic (postural) hypotension

25
Venous collapse in neck can be used to
Estimate central venous pressure
26
What causes jugular vein to collapse
Pressure outside vein being greater than pressure inside vein
27
Skeletal muscle pump
Contracts around vein squashing the blood inside upwards towards heart as blood can't flow backwards - increases venous return
28
Things of significance to skeletal muscle pump
Rhythmic (good) vs static (bad) exercise Heat Deep vein thrombosis Varicose veins (swollen)
29
Respiratory pump
With each inhalation pressure in the thorax decreases which increases the pressure gradient resulting in more venous return
30
Venomotor tone
State of contraction of the smooth muscle surrounding the venules and veins - mobilises capacitance
31
Systemic filling pressure
Pressure created by ventricle and transmitted through vascular tree to the veins (usually 5mmHg)
32
Clotting involves
Formation of platelet plug and fibrin clot
33
How is fibrin made
Made from fibrinogen by the action of thrombin
34
Blood flow is so slow in capillaries that it is in danger of
Clotting
35
Effect of stopping blood from contacting collagen
No platelet aggregation
36
Prostacyclin and NO
Inhibit platelet aggregation
37
Tissue factor pathway inhibitor (TFPI)
Stops thrombin production
38
Thrombomodulin
Binds to thrombin and inactivates it
39
Heparin
Inactivates thrombin
40
Plasminogen activator
Digests clot
41
What exhibits anti-clotting mechanisms
Endothelium