Primer 9 Flashcards Preview

DIT Primers 1-11 (MS ODD; LS EVEN) > Primer 9 > Flashcards

Flashcards in Primer 9 Deck (17):
1

Structures Derived from Branchial Pouches 1-4

1: mastoid air cells, middle ear cavity, eustacian tubes

2: lining of palatine tonsils

3: Thymus, Inferior* parathyroid

4: Superior parathyroid

2

Contents of cavernous sinus:

CN III, IV, V1, V2, VI
Internal carotid artery

3

4 key clinical features of osteogenesis imperfecta:

1. Blue sclera
2. Brittle bones--> many fractures
3. Dental irregularities
4. Hearing loss

4

Tamsulosin: MOA and clinical use?

Selective a-1AD blocker (localized to prostate)
TX: BPH only; has less effect on BP!

5

List 3 selective a-1 blocker drugs and their effects + clinical uses:

DECREASE TPR (BP), Bladder sphincter tone:
1. Parasosin
2. Doxasosin
3. Terasosin

TX: HTN, BPH

6

3 ADRS of a-1 antagonists:

1. Postural HypoTN
2. Reflex tachy
3. Rebound HTN with rapid w/drawal

7

2 Nonspecific a antagonists, their clinical use

1. Phenoxybenzamine- irreversible binding to receptor--Dx. pheochromocytoma
2. Phentolamine

8

3 Nonspecific b-blockers + Tx:

1. Propranolol: anxiety, HTN, ~CHF
2. Timilol- glaucoma
3. Nadolol- Glaucoma

9

2 Selective b-1 blockers:

Metorolol, Atenolol

10

B-Blockers that act as non-specific partial agonists (2):

1. Acebutolol
1. Pindolol

11

2 mixed a-1, b-1 blockers:

Carvedelol, Labetalol

12

Can b-blockers cause erectile dysfunction?

NO: remember "POINT AND SHOOT!"-- doesn't make sense!

13

4 ADRs associated with B-Blockers:

1. Bronchoconstriction
2. Rebound Tacky, HTN, Arrythmia
3. Decrease blood glucose + inhibit sympathetic response to hypoglycemia
4. Bradycardia, AV block

14

4 CI's for B-blocker use:

1. Asthma, COPD
2. DM on meds
3. Cocaine OD (unbalanced a-1 activation!)
4. CHF patients in acute attack

15

6 general clinical uses for b-blockers:

1. HTN
2. CHF
3. Supraventricuar Tachy
4. Angina
5. MI
6. Glaucoma

16

Medical treatment and diagnosis of pheo:

a-agonists!

17

Drug used to treat BPH and its moa?

Tamsulosin; selective a-1AD block!