principles of nervous system 1 Flashcards

1
Q

What is a neuron?

A

functional unit of the nervous system

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2
Q

What are neuroglia?

A

support neurons

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3
Q

What are the 5 parts of a neuron?

A
  • soma/cell body
  • dendrites
  • axon hillock
  • axon/nerve fibre
  • axon terminals
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4
Q

Describe the soma/cell body of a neuron

A
  • contains nucleus
  • synthesis of proteins (lots of ER)
  • cellular metabolism (lots of mitochondria)
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5
Q

Describe the dendrites of a neuron

A
  • receives inputs
  • convey info towards soma
  • large SA (spines) for synapse formation
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6
Q

Describe the axon hillock of a neuron

A
  • origin of the axon
  • very excitable
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7
Q

Describe the axon/nerve fibre of a neuron

A
  • transmits action potential
  • usually only one (althoug may branch)
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8
Q

Describe the axon terminals of a neuron

A
  • synpase on other neurons/effector organs
  • may form specialised sensory endings
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9
Q

What is a unipolar neuron?

A
  • one axon only
  • we have pseudounipolar
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10
Q

Give examples of pseudounipolar neurons?

A
  • primary sensor neurons
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11
Q

Where are the cell bodies of our pseudounipolar neurons found?

A

dorsal root ganglia

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12
Q

What is a bipolar neuron?

A

one axon and one dendrite

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13
Q

Give examples of bipolar neurons

A
  • specialised sensory neurons
  • found in retina, olfactory epithelia
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14
Q

What are multipolar neurons?

A

one axon and multiple dendrites

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15
Q

Give examples of multipolar neurons

A
  • majority of neurons in brain
  • motor neurons
  • autonomic ganglia
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16
Q

How big usually are myelinated axons?

A

1-10 micrometers diameter

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17
Q

How big usually are unmyelinated axons?

A

under 1 micrometer diameter

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18
Q

What are 3 types of neuroglia?

A
  • astrocytes
  • oligodendrocyte
  • microglia
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19
Q

What are the functions of astrocytes?

A
  • structural support
  • scaffold for neurons during development
  • supply nutrients
  • maintain ionic gradients
  • neurotransmitter uptake
  • repair of nervous system
  • form barrier around vessels
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20
Q

What do oligodendrocytes do?

A

myelinates axons

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21
Q

What do microglia do?

A

act as immune cells
- secrete cytokines
- phagocytic
- cytotoxic
promote repair

22
Q

What are the neuroglia of the peripheral nervous system (PNS)

A

schwann cells

23
Q

What are the functions of schwann cells?

A
  • myelinate axons
  • secrete cytokines, phagoytic
  • regeneration (provide substrate for axon to grow along)
24
Q

What constitutes the central nervous system?

A
  • brain
  • spinal cord
25
What constitutes the peripheral nervous sytem?
communication between CNS and periphery
26
What is the most superior part of the brain called?
dorsal surface
27
What is the brain divided into?
- forebrain - midbrain - hindbrain
28
What is grey matter in the brain?
- neuronal cell bodies - synapses - dendrites
29
What is white matter in the brain?
myelinated axons
30
What makes up the forebrain?
- cerebral hemispheres - thalamus - hypothalamus
31
What makes up the hindbrain?
- pons - medulla - cerebellum
32
Describe the cerebral hemispheres
- outer grey matter is cerebral cortex - 10-20 billion neurons - 2.5mm thick - divided into lobes
33
What are the functions of the cerebral hemispheres?
- processing motor and sensory information (20%) - cognition (80%)
34
Describe the thalamus
- relay centre of brain - paired structure - centrally located - sensory info passes via thalamus before reaching cortex
35
Describe the hypothalamus
- important in homeostasis - sits below thalamus - controls autonomic and endocrine nervous systems
36
What is the brainstem formed by?
midbrain and hindbrain
37
What does the brainstem do?
- connects cortex to spinal cord - controls respiration and cardiovascular systems
38
What does the cerebellum do?
coordinate muscular activity
39
Where does the spinal cord start and go to?
from atlas (C1) to first/second lumbar vertebra (L1-L2)
40
Where does the spinal cord sit?
within vertebral canal
41
What are the functions of the spinal cord?
- conveys info - involved in reflexes
42
What are the segments of the spinal cord called from top to bottom?
- cervical - thoracic - lumbar - sacral
43
Describe the spinal cords anatomy
- inner core of grey matter - outer white matter - efferent axons exit ventrally - afferent axons enter dorsally (via peripheral nerves)
44
How are axons organised?
into fascicles
45
What are the layers of axons from outside to in?
- epineurium - perineurium - endoneurium
46
What are the two components of the peripheral nervous system?
- somatic (voluntary) - autonomic (involuntary)
47
What does the somatic component of the nervous system supply?
- skeletal muscles - sensory from skin, muscles and joints
48
What does the autonomic component of the nervous system supply?
- viscera - smooth muscle - glands and vessels
49
Where do all peripheral nerves arise from?
- brain or brainstem as cranial nerves - spinal cord as spinal nerves
50
What do spinal nerves provide?
- motor supply - sensory (somatic) supply - sympathetic (autonomic) supply