Principles of the Endocrine System

Question 1

what is the main goal of the endocrine system?

Answer 1

maintain homeostasis

Question 2

what are the 3 types of hormones (based on synthesis)?

Answer 2

1. amine hormones
2. peptide hormones
3. steroid hormones

Question 3

what are the 3 receptor types hormones bind to?

Answer 3

1. Gpcr
2. Receptor tyrosine kinases
3. nuclear

Question 4

what are 3 inputs that trigger hormone release

Answer 4

1. other hormones
2. ions/nutrients
3. n-transmitters

Question 5

how can you assess endocrine function of a hormone?

Answer 5

dose response curve

Question 6

what is the threshold of a DRC?

Answer 6

the concentration of the compound at which you first see an effect.

Question 7

what is the EC50 on a DRC?

Answer 7

the dose that gives you 50% of the total effect (or binding)

Question 8

what is the max effect on a DRC?

Answer 8

the lowest concentration/dose that will produce a maximal result.

Question 9

what are 3 reasons you would see alterations in hormone response?

Answer 9

1. change in no. of receptors
2. change in no. of target cells
3. change in another hormone system