PRINCIPLES OF VARIATIONS Flashcards

1
Q

Father of EXPERIMENTAL genetics?

A

Morgon

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2
Q

Father of genetics?

A

Mendel

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3
Q

Father of modern Genetics?

A

W.Bateson

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4
Q

Father of genetics -

A

Mendel

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5
Q

Punnett square-

A

RC Punnett

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6
Q
  • Chromosomal theory of Inheritance-
A

Sutton & Boveri

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7
Q

Re-discovery of Mendel’s work -

A

De vries, Tschmark, Correns

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8
Q

term ‘LINKAGE -

A

TH Morgan

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9
Q

who named ‘X-Body’ ?

A

Henking

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10
Q

Mendel’s working years?

A

1856-1863

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11
Q

2 laws of Mendel to understand monohybrid cross?

A
  1. Law of dominance
  2. Law of segregation
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12
Q

Mendel ka esa law jaha there are no exceptions…?

A

Law of Segregation

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13
Q

Exceptions of Law of Dominance?

A

Incomplete and Co-dominance

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14
Q

Example of incomplete dominance?

A

Mirabilis jalapa ( 4 o clock)
Antirrhinum majus (Snapdragon)

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15
Q

Examples of Co dominance?

A

AB blood group
Sickel cell anaemia
Coat colour in cattle

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16
Q

Multiple allele eg?

A

ABO blood group

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17
Q

Polygenic INHERITANCE eg?

A

Human skin colour, weight, height, eye colour

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18
Q

Pleiotropic gene eg?

A

Phenylketonuria, sickle cell anaemia

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19
Q

Sex determination in humans?

A

Homozygous
XX FEMALE
XY- MALE

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20
Q

Sex determination in grasshopper?

A

Heterozygous
XX- FEMALE
XO- MALE

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21
Q

Sex determination in Birds?

A

ZZ- MALE
ZW- FEMALE

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22
Q

Linkage discovered by? In?

A

Morgan, drosophila

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23
Q

Independent assortment- how many types of gametes?
Linkage how many types of gametes?

24
Q

Linkage inversely proportional to?

A

Distance between genes and crossing over

25
Examples of X linkage? X linkage is also known as?
Haemophilia, colour blindness, eye colour in drosophila. Sex linkage
26
How many types of mutation? (2)
CHROMOSOMAL , GENE 1. EUPLOIDY 1. POINT 2. ANEUPLOIDY 2. FRAMESHIFT
27
Sex linked recessive diseases?
HINDUSTAN CONVENT SCHOOL COLOUR BLINDNESS, HAEMOPHILIA
28
Autosomal recessive diseases?
Sickle cell anemia, PKU, thallasemia
29
Sickel cell anemia...?
Substitution of Glutamic acid to Valine at 6th Hb
30
Thalassemia?
Hb me chain kam tha
31
Pku?
Generally Phenylalanine converts to tyrosine in the presence of an enzyme But here, phenylalanine gets converted to phenyl pyruvic acid
32
Down syndrome?
3 copies of 21st Trisomy chromosome
33
Klinefelter?
Males normally- XY ...here XXY
34
Turner syndrome?
Female generally XX, here, XO
35
who coined the term genetics?
W.Bateson
36
Artificial selection was done with?
Indian breeds example- Sahiwal cows in Punjab
37
Dna total length?
2.2 metre
38
how many types of linkages are there...and what are they?
complete , incomplete
39
Law of inheritance proposed by?
Gregor mendel
40
What did MENDEL construct? N how?
Cross pollination using true breeding pea line Artificially
41
Mendel selected how many contrasting traits?
14 true breeding contrasting traits
42
What is true breeding line?
Performing self pollination continuously for homozygous traits, due to which shows stable trait inheritance and expression for several generations
43
What was performed in INHERITANCE OF 1 GENE?
Single char considered Performed monohybrid cross for all characters
44
Punett was?
british geneticist
45
exception of law of independent assortment?
linkage
46
VIMP BLOOD EXAMPLE ABO BLOOD GROUP? AB BLOOD GROUP? ABO BLOOD GROUP IS REGULATED BY? HOW MANY ALLELES?
Multiple allelism, Co-dominance I gene has 3 alleles
47
I gene decides?
Antigen (polymer of sugar)
48
In pleiotropy what is involved ?
product of gene in diff metabolic pathway
49
Single gene mutation causes?
1. Phenylketonuria 2. Mental retardation 3. Depigmentation
50
Which types of crosses are based on the inheritance of a single gene?
Dominance Incomplete Dominance Codominance Multiple Allelism Pleiotropy
51
intermediate skin colour is also k/as as?
mulatto
52
what is under incomplete linkage?
loosely linked, tightly linked
53
Morgan's experiment was based on how many characters?
The linkage was based on 2 char- body colour and wing type sex linked inheritance was based on 1 char- eye colour
54
MORGAN EXPERIMENT...BODY COLOUR? EYE COLOUR? WING SIZE?
BROWN YELLOW WILD MUTANT RED WHITE WILD MUTANT NORMAL MINIATURE WILD MUTANT
55
representation of position of linked genes on a chromosome is first given by?
Morgan's student Alfred Sturtevent
56
how many types of mutation (2)?
1.