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Flashcards in Prostate ca Deck (3):
1

Abiratarone

Peripheral androgen synthesis inhibitor
17CYP pathway
Inhibits 17α-hydroxylase (CYP17), key enzyme in steroid synthesis
Keyside effects
- Fluid retention, hypertension
- Hypokalemia
Must be used in combination with prednisolone

2

GnRH antagonist

Degarelix

3

GnRH agonist

goserelin, leuprolide