Flashcards in Prostatic Hyperplasia Deck (10):
Increase in the size of the prostatic gland without malignancy
Glandular epithelial cells and stroll cells undergo hyperplasia
Usually the MEDIAN LOBE is affected
Not fully known.
Assumed relationship to androgens, possibly promoting cell proliferation in the prostate.
Affects QOL of:
40% of men in 50s
90% of men in 90s
Straining (I-PSS grading)
Alpha blockers (doxazosin) to those with severe voiding problems.
5-alpha reductase inhibitor (finasteride)
Surgery: Large prostate/failure to respond; transurethral resection of the prostate.
Recurrent UTI. Bladder calculi.
Treatment - example of alpha blocker
Doxazosin or Tamsulosin