Protein 3D Conformation Flashcards Preview

BB1702 Biochemistry: Structure and Function > Protein 3D Conformation > Flashcards

Flashcards in Protein 3D Conformation Deck (7)
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1

What are the different classifications of proteins?

Globular, fibrous, and membrane proteins

2

Describe myoglobin

A monomeric, globular protein composed of 123 amino acids. Contains the prosthetic group haem.

Only two polar residues on the interior; two histidine residues.

3

What does haem consist of?

Protoporphyrin IX and a central iron atom. The protoporphyrin is made up of four pyrrole rings linked by methine bridges to form a tetra-pyrrole ring.

4

Which iron state in haem is capable of binding oxygen?

Fe2+

5

The ____ in haem can form two additional bonds, one each side of the ____ _____. These binding sites are called the _____ and _____ coordination sites.

The iron in haem can form two additional bonds, one each side of the haem plane. These binding sites are called the fifth and sixth coordination sites.

6

In myoglobin, the _____ coordination site is occupied by the _______ ring of a ________ residue from the protein. The ________ is referred to as the proximal ________.

In myoglobin, the fifth coordination site is occupied by the imidazole ring of a histidine residue from the protein. The histidine is referred to as the proximal histidine.

7