Proteins Flashcards

(59 cards)

1
Q

CHON is called amphoteric because

A

Has positive and negative charges

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2
Q

CHON provide ______ of the total daily body energy requirement

A

12-20%

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3
Q

CHON are _______ of the cell’s dry weight

A

50-70%

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4
Q

Proteins come from greek word

A

“proteis”- first rank of importance

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5
Q

Actual 3-dimensional configuration of protein

A

Tertiary structure

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7
Q

Winding of the polypeptide chain: what structure?

A

Secondary structure

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8
Q

Glucogenic amino acids generate what precursors of glucose?

A

Pyruvate and citric avid cycle intermediates

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9
Q

Linear sequence of the amino acid

A

Primary structure

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10
Q

Balance between anabolism and catabolism

A

Nitrogen balance

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11
Q

Anabolism > catabolism

A

Positive Nitrogen Balance

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12
Q

Catabolism > anabolism

A

Negative Nitrogen Balance

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13
Q

Percent of nitrogen content in serum CHON

A

16%

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14
Q

CHON = _____ x N

A

6.25

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15
Q

Other name of prealbumin

A

Transthyretin

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16
Q

RV of prealbumin

A

18-45mg/dl

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17
Q

General transport CHON

A

Albumin

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18
Q

Folding pattern of protein

A

Tertiary structure

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19
Q

Serves a circulating reservoir of AA

A

Albumin

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20
Q

CHON that binds quinidine

A

a1- acid glycoprotein

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21
Q

Other name for alpha1- acid glycoprotein

A

Orosomucoid

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22
Q

Neutralizes neutrophil elastase that destroy lung alveoli

A

Alpha1-antitrypsin

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23
Q

Major inhibitor of protease activity

A

Alpha-1 antitrypsin

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24
Q

Transport T4T3 and retinol

A

Prealbumin

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25
Q

Maintains osmotic/oncotic pressure

27
CHON is synthesized in
Liver
28
Lowest level of Albumin is seen in
Nephrotic syndrome
29
Maternal serum AFP is done between
15 and 20 weeks of gestation
30
As landmark to confirm that the specimen is CSF
Prealbumin
31
Useful diagnostic tool in neonates with bacterial infections
Alpha-1 acid glycoprotein
32
Half life of prealbumin
2 days
33
Major form of PSA found in human sera
Alpha-1 antichymotrypsin
35
CHON that is associated with Alzheimer's disease
Alpha-1 antichymotrypsin
36
Indicator of nutrition
Albumin
37
Sensitive and highly prognostic marker of cystic fibrosis
Albumin
38
Prealbumin is rich in
Tryptophan and 0.5% CHO
39
Binds heme
Hemopexin
40
Ceruloplasmin imparts what color in protein?
Blue
41
Increase level of AFP is used to assess ______ of fetus
Neural tube effects
42
For diagnosis of early hemolysis
Hemopexin
43
Level of ceruloplasmin in Wilson's diease
0.1 g/L
44
Copper deposition in cornea of Wilson's disease is what you called?
Kayser-Fleisher rings
45
Reference value for Ceruloplasmin
18-45mg/dL
46
B2- microglobulin is needed in production of what cells
CD8 cells
47
CHON with affinity to vitamin D and actin
Group-specific component globulin
48
Alpha-1 antichymotrypsin is a serine proteinase with
Cathepsin G
49
Other name of transferrin
Siderophilin
50
Light chain component of HLA
B2- microglobulin
51
Alpha-2 macroglobulin inhibits
Trypsin, pepsin and plasmin
52
Major component of B2- microglobulin
Transferrin
53
Early warning test for person at risk of coronary artery disease
CRP
54
Marker for long term prognosis of cardiovascular disease
Fibrinogen
55
Most abundant complement in serum
C3
56
CHON that is important in pathogenesis of age-related macular degeneration
C3
57
Has greatest affinity to progesterone
Alpha-1 acid glycoprotein
58
Gold standard in acute coronary syndrome
Troponin
59
General scavenger molecule
CRP
61
In extensive coagulation, fibrinogen is
Decrease
63
CHON helps in evaluation of Intravascular hemolysis
Haptoglobin
66
Ketogenic Amino acids are degraded to
Acetyl CoA