PROTEINS & AMINO ACIDS Flashcards
(38 cards)
most abundant biological macromolecules
Proteins
refers to the exact sequence of amino acids along a protein chain
Primary structure
refers to the bending or folding of the long chain of amino acids
ex: pleated sheets / alpha helix
Secondary structure
the further folding; 3D folding pattern because of the interactions between the side chains in the amino acids
Tertiary structure
aggregation of more than one polypeptide chain such as hemoglobin
Quaternary structure
GENERAL STRUCTURE OF AMINO ACID
Right: Carboxylic group
Left: Amino group
Side chain
all amino acids except _____ are chiral and have the L configuration
Glycine
how to determine if an amino acid has an L configuration
if amino acid is on left side and if is chiral
are molecules with zero functional group with a positive and negative charge which are equal to zero
Zwitterions
there are 22 amino acids but only 20 amino acids comprise the building blocks for protein synthesis. What are the remaining two
Hydroxyproline
Cystine
a nonessential amino acid necessary for the construction of the body’s major structural protein collagen
Hydroxyproline
is present essentially in all tissues and all genetic types of collagen
Hydroxyproline
Defects in _____ synthesis lead to bruising, internal bleeding, breakdown of connective tissue of the ligaments and tendons, and increased risk to blood vessel damage
Collagen synthesis
precursor of Hydroxyproline
Proline
is an amino acid found in digestive enzymes, cells of the immune system, skeletal & connective tissues, skin, and hair
Cystine
the conversion of proline to hydroxyproline requires _____
vitamin C
hair and skin are __% - __% cystine
10% -14%
connects cysteine molecules
Sulfide bond
amino acids are classified based on their __ groups
R groups
specific amide bond that links the two amino acids together forming peptide or polypeptide chain
Peptide bonds
peptide is form the greek word _____, meaning digestion/digested
peptos
are fragments of proteins produced during protein digestion
peptides
Peptide has partial double bond character; ROTATION AT THE C-N BOND IS NOT POSSIBLE
2 amino acids
Dipeptide