PSA Flashcards
(25 cards)
Drugs to stop in acute renal failure
ACEI/ARB
Metformin
Allopurinol (reduce)
NSAIDS
Drugs causing hypoglycaemia
Pioglitazone
Sulphonylureas (gliclazide, tolbutamide)
Insulin
Drugs causing urinary retention
Anticholonergics GA Benzos NSAIDs CCBs Anitihistamines Alcohol
Drugs causing confusion
Opiates Anticholinergics Antipsychotics Antidepressants Anticolvulsants Antihistamines Metacloperamide
Starting dose simvastatin
Primary prevention - 20mg ON
Established CVD - 80mg ON
HTN - First Line Drugs
<55 - ACEI
>55 - CCB
Afrocaribean - CCB
Diabetic - ACEI
Folic acid doses
Low risk - 400mcg
High risk - 5mg
Bisphosphonates - patient advice
Take 30 mins before food or other drugs
Sit upright for 30 mins
Take with plenty of water
Gentamycin - interpretation of levels
Peak level high/low - change dose
Trough level high/low - change frequency
CYP Inducers
Phenytoin Carbamazepine Barbiturates Rifampacin Alcohol (chronic) Sulphonyureas (gliclazide)
CYP Inhibitors
Grapefruit Omeprazole Disulfiram EtOH (acute) Valproate Isoniazid Ciprfloxacin + Cimetidine Erythromycin (and other macrolides) Sulphonamides
Lithium - monitoring
Before starting: BMI, ECG, U&Es, FBC
6/12: BMI, U&Es, TFTs
Levels - minimum 3/12
Drugs causing neutropenia
Chemotherapy
Carbamazepine
Surgical VTE Prophylaxis with a needle phobia
Apixaban 2.5mg BD
or
Rivaroxiban 10mg OD
Drugs causing hyperkalaemia
I SHAT one when I saw they had hyperkalaemia
SHAT Spironolactone / Eplerenone Heparins ACEi Tacrolimus / Ciclosporin
Surgery - drugs to stop
Anti platelets (7/7)
Hypoglycaemics (morning of)
OCP/HRT (4/52)
Warfarin (5/7)
Drugs causing hyponatraemia
Thiazides
SSRIs
ACEI/ARB
INR >1.5 before surgery
phytomenadione (vitamin K) 5mg PO
Daily potassium requirements
1mmol/kg/day
Missed OCP pills
Take as soon as remember
If this is the next day then take two pills that day
No other contraception needed
Statins - myalgia and raised CK
If CK > 5x upper limit then stop
If symptoms resolve then re-start at lower dose
Causes of ankle oedema
Amlodipine
Naproxen
Initial management of DKA
Fluid resus - 1l 0.9% NaCl over first hour
Fixed rate insulin infusion - Actrapid 0.1u/kg/hr IV
Continue current long-acting insulin
Management of Neuroleptic Malignant Syndrome
Procyclidine
