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Flashcards in PSA Deck (25)
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1

Drugs to stop in acute renal failure

ACEI/ARB
Metformin
Allopurinol (reduce)
NSAIDS

2

Drugs causing hypoglycaemia


Pioglitazone
Sulphonylureas (gliclazide, tolbutamide)
Insulin

3

Drugs causing urinary retention

Anticholonergics
GA
Benzos
NSAIDs
CCBs
Anitihistamines
Alcohol

4

Drugs causing confusion

Opiates
Anticholinergics
Antipsychotics
Antidepressants
Anticolvulsants
Antihistamines
Metacloperamide

5

Starting dose simvastatin

Primary prevention - 20mg ON
Established CVD - 80mg ON

6

HTN - First Line Drugs

<55 - ACEI
>55 - CCB

Afrocaribean - CCB
Diabetic - ACEI

7

Folic acid doses

Low risk - 400mcg
High risk - 5mg

8

Bisphosphonates - patient advice

Take 30 mins before food or other drugs

Sit upright for 30 mins

Take with plenty of water

9

Gentamycin - interpretation of levels

Peak level high/low - change dose

Trough level high/low - change frequency

10

CYP Inducers

Phenytoin
Carbamazepine
Barbiturates
Rifampacin
Alcohol (chronic)
Sulphonyureas (gliclazide)

11

CYP Inhibitors

Grapefruit
Omeprazole
Disulfiram
EtOH (acute)
Valproate
Isoniazid
Ciprfloxacin + Cimetidine
Erythromycin (and other macrolides)
Sulphonamides

12

Lithium - monitoring

Before starting: BMI, ECG, U&Es, FBC
6/12: BMI, U&Es, TFTs

Levels - minimum 3/12

13

Drugs causing neutropenia

Chemotherapy
Carbamazepine


14

Surgical VTE Prophylaxis with a needle phobia

Apixaban 2.5mg BD
or
Rivaroxiban 10mg OD

15

Drugs causing hyperkalaemia

I SHAT one when I saw they had hyperkalaemia

SHAT
Spironolactone / Eplerenone
Heparins
ACEi
Tacrolimus / Ciclosporin

16

Surgery - drugs to stop

Anti platelets (7/7)
Hypoglycaemics (morning of)
OCP/HRT (4/52)
Warfarin (5/7)

17

Drugs causing hyponatraemia

Thiazides
SSRIs
ACEI/ARB

18

INR >1.5 before surgery

phytomenadione (vitamin K) 5mg PO

19

Daily potassium requirements

1mmol/kg/day

20

Missed OCP pills

Take as soon as remember
If this is the next day then take two pills that day
No other contraception needed

21

Statins - myalgia and raised CK

If CK > 5x upper limit then stop
If symptoms resolve then re-start at lower dose

22

Causes of ankle oedema

Amlodipine
Naproxen

23

Initial management of DKA

Fluid resus - 1l 0.9% NaCl over first hour
Fixed rate insulin infusion - Actrapid 0.1u/kg/hr IV
Continue current long-acting insulin

24

Management of Neuroleptic Malignant Syndrome

Procyclidine

25

Analgaesia in renal failure

Avoid NSAIDs
Oxycodone > morphine - has hepatic metabolism so won't accumulate