psoriasis

Question 1

genetic assocs

Answer 1

HLA B13
HLA B17
HLA Cw6

Question 2

immunology pathphys

Answer 2

abnormal T cell activity stimulates keratinocyte proliferation

Question 3

subtypes

Answer 3

plaque psoriasis
flexural psoriasis
guttate psoriasis
pustular psoriasis

Question 4

guttate psoriasis

Answer 4

triggered by streptococcal infection

multiple red teardrop lesions appear on body

Question 5

features

Answer 5

well demarcated red scaly patches

Question 6

exacerbating factors

Answer 6

trauma
alcohol
withdrawal systemic steroids
infection

Question 7

exacerbating factors - drugs

Answer 7

beta blockers
antimalarials
lithium 
NSAIDs
ACEI

Question 8

topical treatment

Answer 8

1/ potent steroid OD and vit D OD, applied at different times
2/stop steroid, applt vitD 2x daily
3/ stop vitD, apply potent steroid 2x daily

Question 9

phototherapy

Answer 9

narrowband UVB light

Question 10

systemic therapy

Answer 10

1/ methotrexate

2/ciclosporin

Question 11

biologic therapy

Answer 11

infliximab

etanercept

Question 12

topical steroids - mild

Answer 12

hydrocortisone 0.5%

Question 13

topical steroids - moderate

Answer 13

eumovate

Question 14

topical steroids - potent

Answer 14

betnovate

Question 15

topical steroids - very potent

Answer 15

dermovate