toxic epidermal necrolysis Flashcards

1
Q

what

A

lifethreatining skin disoderder most commonly 2ry to drug reaction

skin develops scalded appearance oevr extensive area

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2
Q

feaures

A

scalded appearance skin
systemically unwell
positive Nikolsky’s sign

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3
Q

Nikolsky’s sigh

A

epidermis seperates with mild lateral pressure

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4
Q

drugs known to induce TEN

A
phenytoin 
sulphonamides
allopurinol 
penicillins
carbamezapine
NSAIDs
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5
Q

Mx

A

stop precipitating factor
supportive care
IVIg

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6
Q

potential complication

A

volume loss and electrolyte derrangement

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