PSY240 5. Substance Abuse Flashcards

(248 cards)

1
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Externalizing Disorders

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Externalizing Disorders

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Externalizing Disorders

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Substance use

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• Substance: Any product with psychoactive effects • ~50% have tried an illegal substance (U.S.)
– 15% in the past year
• Problematic use differs
• Across the lifespan
• Across different cultures
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5
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Substance use

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6
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Substance use

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7
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Substance use

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8
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Categories of Substances

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  1. CNS Depressants
  2. CNS Stimulants
  3. Opioids
  4. Hallucinogens and phencyclidine (PCP) 5. Cannabis
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9
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Categories of Substances

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10
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Categories of Substances

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11
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Categories of Substances

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12
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Substances Used

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13
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Substances Used

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14
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Substances Used

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15
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Frequency of DSM-IV Disorders

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16
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Frequency of DSM-IV Disorders

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17
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Frequency of DSM-IV Disorders

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18
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Frequency of DSM-IV Disorders

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19
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Substance-Related Conditions (DSM-IV)

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• Substance intoxication:
– Maladaptive symptoms due to effect of
substance on CNS
• Substance withdrawal:
– Distress/impairment in function due to cessation/reduction of use
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20
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Substance-Related Conditions (DSM-IV)

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21
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Substance-Related Conditions (DSM-IV)

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22
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Substance-Related Conditions (DSM-IV)

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23
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Substance-Related Conditions (DSM-IV)

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• Substanceabuse:
– Recurrent substance useharmful consequences
• Substancedependence:
– Recurrent substance use
• physiological dependence
• Significant impairment
• Significant distress
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24
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Substance-Related Conditions (DSM-IV)

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Substance-Related Conditions (DSM-IV)
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Substance-Related Conditions (DSM-IV)
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Substance Abuse (DSM-IV)
1+ symptoms occurs during a 12-month period: 1. Failure to fulfill important obligations 2. Repeated use in hazardous situations 3. Repeated legal problems 4. Use despite social problems • Causes significant impairment or distress
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Substance Abuse (DSM-IV)
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Substance Abuse (DSM-IV)
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Substance Abuse (DSM-IV)
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Substance Abuse (DSM-IV)
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Substance Dependence (DSM-IV-TR)
Maladaptive pattern of substance use (3+): 1. Tolerance 2. Withdrawal 3. Substance taken in more/longer than intended 4. Persistent desire/unsuccessful efforts to cut back/control 5. Substance use is time-consuming 6. Important activities are reduced because of substance use 7. Use continued despite persistent problems
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Substance Dependence (DSM-IV-TR)
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Substance Dependence (DSM-IV-TR)
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Substance Dependence (DSM-IV-TR)
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Substance Dependence (DSM-IV-TR)
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Substance Dependence (DSM-IV-TR)
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Substance Dependence (DSM-IV-TR)
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CHANGES IN DSM-5: Criteria and Terminology
Diagnostic Thresholds
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CHANGES IN DSM-5: Criteria and Terminology
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CHANGES IN DSM-5: Criteria and Terminology
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CHANGES IN DSM-5: Criteria and Terminology
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CHANGES IN DSM-5: Criteria and Terminology
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CHANGES IN DSM-5: Criteria and Terminology
• Severity is based on the number of criteria endorsed: – Mild disorder: 2–3 criteria – Moderate disorder: 4–5 criteria – Severe disorder: 6+ criteria
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CHANGES IN DSM-5: Criteria and Terminology
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CHANGES IN DSM-5: Criteria and Terminology
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CHANGES IN DSM-5: Criteria and Terminology
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CHANGES IN DSM-5: Criteria and Terminology
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Changes in DSM-5
DSM-IV | DSM-5
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Changes in DSM-5
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Changes in DSM-5
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Changes in DSM-5
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Changes in DSM-5
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Remission Status
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Remission Status
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Remission Status
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Alcohol Use
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Alcohol Use
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Alcohol Use
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Alcohol Use
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Alcohol Intoxication
* Mood | * Behaviour • Physiology • Cognition
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Alcohol Intoxication
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Alcohol Intoxication
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Alcohol Intoxication
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Alcohol Intoxication
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Common Problems in Alcohol Use Disorder
* 80% Engaged in daily or weekly heavily drinking • 70% Consumed 1/5 (26er) of liquor in one day • 62% Family objects * 59% Perceives self as an "excessive drinker" * 31% Was arrested while drinking * 21% Wanted to stop drinking but couldn't • 14% Continued to drink with serious illness
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Common Problems in Alcohol Use Disorder
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Common Problems in Alcohol Use Disorder
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Common Problems in Alcohol Use Disorder
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Common Problems in Alcohol Use Disorder
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Long-term Effects of Alcohol Abuse
* Low-grade hypertension * Paranoia * Deficits in memory and cognition * Wernicke-Korsakoff ’s syndrome * Alcohol-induced dementia * Alcohol-induced persisting amnesic disorder * Fetal alcohol syndrome
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Long-term Effects of Alcohol Abuse
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Long-term Effects of Alcohol Abuse
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Long-term Effects of Alcohol Abuse
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Long-term Effects of Alcohol Abuse
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Benzodiazepines and Barbiturates
• Benzodiazepines: Xanax, Valium, Halcion, Librium • Barbiturates: Quaaludes – Legally manufactured – Sold by prescription
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Benzodiazepines and Barbiturates
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Benzodiazepines and Barbiturates
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Benzodiazepines and Barbiturates
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Benzodiazepines and Barbiturates
Signs of use/intoxication • Mild euphoria • Relief of tension, anxiety • Slurred speech • Poor motor coordination • Impaired judgment • Poor concentration • Sleepiness
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Benzodiazepines and Barbiturates
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Benzodiazepines and Barbiturates
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Benzodiazepines and Barbiturates
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Benzodiazepines and Barbiturates
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Benzodiazepines and Barbiturates
Long-term effects • Chronic tiredness • Breathing disorders • Vision Problems
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Benzodiazepines and Barbiturates
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Benzodiazepines and Barbiturates
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Benzodiazepines and Barbiturates
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Benzodiazepines and Barbiturates
Patterns of problematic use: | 1. Adolescents’ recreational use 2. Increasing prescription dosage
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Benzodiazepines and Barbiturates
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Benzodiazepines and Barbiturates
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Benzodiazepines and Barbiturates
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Inhalants
* Solvents | * Anesthetic gases and nitrates
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Inhalants
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Inhalants
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Inhalants
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Inhalants
Signs of use/intoxication • paintorstainsonbodyorclothing • spotsorsoresaroundthemouth • redorrunnyeyesornose • chemicalbreathodor • drunk,dazedordizzyappearance • nausea, loss of appetite • anxiety,excitability,irritability
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Inhalants
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Inhalants
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Inhalants
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Inhalants
``` Harmful Effects • Brain damage, memory loss • Hearing loss, Slurred speech • Nose bleeds, loss of smell • Suffocation, sudden death • Irregular heart beat, heart attack • Nausea, vomiting • Liver damage, kidney damage • Etc… ```
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Inhalants
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Inhalants
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Inhalants
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Inhalants
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Inhalants
``` Chronic use • Respiratory irritations, rashes • Permanent CNS damage, organ failure, death At-risk populations • Prepubescent and early teen boys • Aboriginal youth ```
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Inhalants
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Inhalants
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Inhalants
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Stimulants: Cocaine
``` Affective/Cognitive symptoms: • Euphoria • Affective blunting • Impaired judgment Somatic Symptoms: • Fight-or-flight response • GI symptoms • Seizures, coma ```
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Stimulants: Cocaine
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Stimulants: Cocaine
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Stimulants: Cocaine
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Stimulants: Cocaine
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Stimulants: Amphetamines
``` Uses: • Combat depression, fatigue • Boost energy and self-confidence • Appetite suppressant • Symptoms similar to cocaine intoxication ```
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Stimulants: Amphetamines
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Stimulants: Amphetamines
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Stimulants: Amphetamines
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Stimulants: Amphetamines
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Amphetamines and Neurotransmitters
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Amphetamines and Neurotransmitters
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Amphetamines and Neurotransmitters
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Stimulants: Nicotine
• Affects CNS & PNS • Releases DA, NE, 5-HT, endogenous opioids • Withdrawal symptoms: – https://www.youtube.com/watch?v=a7MIpyUpEcE • No DSM-IV-TR diagnosis Æ new to DSM-5
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Stimulants: Nicotine
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Stimulants: Nicotine
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Stimulants: Nicotine
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Stimulants: Nicotine
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Stimulants: Caffeine
``` • Most heavily used stimulant – ~2 cups / day (U.S.) – 1 cup = 100 mg caffeine • Affects CNS • Increases DA, NE, & 5-HT ```
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Stimulants: Caffeine
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Stimulants: Caffeine
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Stimulants: Caffeine
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Stimulants: Caffeine
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Stimulants: Caffeine
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Opioids
``` Derived from the opiate poppy: – Morphine – Heroin – Codeine – Methadone • Derived naturally from the body: – Endorphins – Enkaphalins ```
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Opioids
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Opioids
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Opioids
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Opioids
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Opioids
Intoxication • Mood • Cognition • Physiology Withdrawal • Mood • Physiology
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Opioids
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Opioids
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Opioids
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Opioids
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Hallucinogens and PCP
``` Hallucinogens • e.g., LSD, MDMA (ecstasy), and peyote. PCP (angel dust) • Snorted or smoked • Not technically a hallucinogen, but has similar effects ```
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Hallucinogens and PCP
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Hallucinogens and PCP
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Hallucinogens and PCP
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Hallucinogens and PCP
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Cannabis
* Intoxication * Mood * Cognition * Physiology * Moderate to high dose may cause * hallucinations * depersonalization * paranoia
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Cannabis
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Cannabis
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Cannabis
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Cannabis
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Non-Substance-Related Addictions
Examples: gambling, sex, exercise, | video games, work, shopping, etc.
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Non-Substance-Related Addictions
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Non-Substance-Related Addictions
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Non-Substance-Related Addictions
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Non-Substance-Related Addictions
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Gambling Disorder
* A pattern of gambling behaviour that causes harm * 12 month Canadian prevalence = ~ 2% (Cox et al., 2005) * DSM Classification * DSM-IV-TR: “Impulse-control disorders NOS” * DSM-5: Non-substance-related disorder
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Gambling Disorder
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Gambling Disorder
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Gambling Disorder
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Gambling Disorder
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DSM-5 Section III Conditions
Hypersexual Disorder: • A pattern of sexual behaviour that is initially pleasurable but that becomes unfulfilling and self-destructive Internet Gaming Disorder: • Persistent and recurrent use of the Internet to engage in games, often with other players
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DSM-5 Section III Conditions
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DSM-5 Section III Conditions
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DSM-5 Section III Conditions
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DSM-5 Section III Conditions
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DSM-5 Section III Conditions
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Concurrent Disorders
Comorbid mental health and substance use problems • Complex and difficult to treat Substance Use Treatment Seekers Psychiatric Treatment Seekers
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Concurrent Disorders
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Concurrent Disorders
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Concurrent Disorders
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Concurrent Disorders: Stress & Trauma
``` Impact influenced by • Stressor • Individual differences • Gender • Age • Genes ```
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Concurrent Disorders: Stress & Trauma
``` Stress/Trauma => Negative Affect / Somatic Symptoms => Poor Coping Skills => Substance Use =>Stress Proliferation => ```
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Concurrent Disorders: Stress & Trauma
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Concurrent Disorders: Stress & Trauma
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Concurrent Disorders: Stress & Trauma
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Concurrent Disorders: Stress & Trauma
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Concurrent Disorders: Stress & Trauma
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Concurrent Disorders: Anxiety & Mood Disorders
``` Anxiety • Risk of substance problems 2-5X higher • In 75% of cases, anxiety came first Bipolar Disorder • Possible overlapping predispositions • A “disorder-inducing disorder” ```
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Concurrent Disorders: Anxiety & Mood Disorders
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Concurrent Disorders: Anxiety & Mood Disorders
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Concurrent Disorders: Anxiety & Mood Disorders
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Concurrent Disorders: Anxiety & Mood Disorders
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Concurrent Disorders: Anxiety & Mood Disorders
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Concurrent Disorders: Psychosis
• Substance use can: – Hasten onset of psychotic disorders – Worsen symptoms and the course of illness – Exacerbate negative consequences
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Concurrent Disorders: Psychosis
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Concurrent Disorders: Psychosis
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Concurrent Disorders: Psychosis
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Cultural Specificity
* Some cultures impose strict sanctions on all drugs * Some cultures view it as a medical problem * Some distinguish soft vs. hard drugs * Some cultures normalize it
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Cultural Specificity
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Cultural Specificity
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Cultural Specificity
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Cultural Specificity
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Societal Costs
• Costs ~$14 billion CAD / year
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Societal Costs
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Motivational Models
• Desire for Mood Alteration – Negative Affect Reduction (Emotionally vulnerable) – Euphoria/Excitement Induction (Antisocial/Impulsive)
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Motivational Models
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Major Dopamine Pathways | AKA “the reward pathway,” “the pleasure centre”
``` Manufactured in • Ventral Tegmental Area (VTA) Released to • Nucleus Accumbens • Prefrontal Cortex ```
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Major Dopamine Pathways | AKA “the reward pathway,” “the pleasure centre”
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Major Dopamine Pathways | AKA “the reward pathway,” “the pleasure centre”
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Major Dopamine Pathways | AKA “the reward pathway,” “the pleasure centre”
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Septal-Hippocampal Area
``` • Connected via GABA-sensitive neurons • ↑ GABA reduces anxiety • ↓ GABA – increases anxiety – increased sensitivity to pain – panic attacks, seizures • Self-medicate with substances ```
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Septal-Hippocampal Area
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Septal-Hippocampal Area
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Septal-Hippocampal Area
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Genetic Factors
Behavioural Genetics Studies • Moderate-to-high heritability • Phenotypes (e.g., impulsivity) also heritable Molecular Genetics Studies • The role of specific genes is unclear • Implicates gene variants linked to DA deficiency
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Genetic Factors
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Genetic Factors
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Genetic Factors
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Genetic Factors
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Psychological Theories
Behavioural • Positive & Negative Reinforcement (self-medication) • Modelling (parents, peers, culture, media) • Maladaptive coping (comorbid social phobia)
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Psychological Theories
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Psychological Theories
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Psychological Theories
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Psychological Theories
``` Dispositional • Trait vulnerabilities • Impulsivity • Tendency to act without planning or restraint • Strongest predictor of substance use • Diathesis for substance use disorders ```
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Psychological Theories
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Psychological Theories
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Sociocultural Theories
``` Adolescent Alcohol Use • Experimentation • Adolescents with alcoholic parents • Stress in family home • Opposite-sex friends ```
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Sociocultural Theories
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Sociocultural Theories
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Sociocultural Theories
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Sociocultural Approaches
* Chronic stress + support/promotion of use * Advertising and media * Gender differences
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Sociocultural Approaches
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Sociocultural Approaches
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Sociocultural Approaches
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Integrative Model
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Integrative Model
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Integrative Model
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Integrative Model
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Treatments
Alcoholics/Narcotics Anonymous • “12-step” programs • Total abstinence • 27% AA members sober after 1 year
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Treatments
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Treatments
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Treatments
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Treatments
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Treatments
Biological Treatments: • Antidepressants & Antianxiety agents • Antagonists (block reinforcing effects) • Agonists (e.g., Methadone)
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Treatments
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Treatments
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Treatments
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Treatments
``` Behavioural • Aversive classical conditioning • Covert sensitization therapy • Cue exposure and response prevention • Controlled Drinking (controversial) ```
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Treatments
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Treatments
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Treatments
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Treatments
Cognitive • Identify and gain control in risk situations Motivational Interviewing (MI) • Therapists express empathy, support self-efficacy • Help clients explore and resolve ambivalence
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Treatments
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Treatments
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Treatments
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