Psych/Neuro

Question 1

Doxepin brand?

Answer 1

Silenor

Question 2

Class of Doxepin?

Answer 2

Tertiary amine TCA

Question 3

Brand of Nortriptyline?

Answer 3

Pamelor

Question 4

Brand of Amitrityline?

Answer 4

Elavil

Question 5

Class of Amitriptyline?

Answer 5

Tertiary amine TCA

Question 6

Class of Nortriptyline?

Answer 6

Secondary amine TCA

Question 7

Which antidepressants cause QT prolongation?

Answer 7

Citalopram and escitalopram

Question 8

Which antidepressants is preferred in cardiac patients?

Answer 8

Sertraline

Question 9

Which antidepressants should you avoid in pregnant patients?

Answer 9

Paroxetine

Question 10

What are the most sedating antidepressants?

Answer 10

Paroxetine, mirtazapine, trazodone

Question 11

What are the most “activating” antidepressants?

Answer 11

Fluoxetine, bupropion

Question 12

Which antidepressants cause less sexual dysfunctions?

Answer 12

Bupropion and mirtazapine

Question 13

Brand of fluoxetine?

Answer 13

Prozac

Question 14

Maximum daily dose of citalopram / escitalopram?

Answer 14

Citalopram = 40mg/day

Escitalopram = 20mg/day

Question 15

Generic of Zyprexa?

Answer 15

Olanzapine

Question 16

Generic of Latuda?

Answer 16

Lurasidone

Question 17

Generic of Invega?

Answer 17

Paliperidone

Question 18

Which anti-psychs have the highest % of QT prolongation?

Answer 18

All psych drugs do, but the highest % are = First gen + Geodon

Question 19

DOC for a patient w/ hisotry of movement disorders and needs to be on an anti-psych?

Answer 19

Quetiapine

Question 20

Trough levels for lithium?

Answer 20

0.6 - 1.2

Question 21

General Tx plan for bipolar?

Answer 21

Mania - valproate, lithium, carbamazepine, lamotrigine

Depression - lithium, lamotrigine

Question 22

5ml of lithium citrate = ____ mg lithium carbonate

Answer 22

300mg

Question 23

General Tx for ADHD?

Answer 23

1. Stimulants
2. Atomoxetine (SNRI)
3. Guanfacine ER (Intuniv) and clonidine ER (Kapvay)

Question 24

Generic of Lunesta?

Answer 24

Eszopiclone

Question 25

Psychosis can occur in parkinson's patients, but also with which meds?

Answer 25

Carbidopa/Levodopa Dopamine agonists: Pramipexole + Ropinirole

Question 26

Brand of benztropine?

Answer 26

Cogentin

Question 27

Purpose of benztropine?

Answer 27

Used for tremors

Question 28

Important parts of Carbidopa/Levodopa dosing?

Answer 28

You need at least 70mg of carbidopa to inhibit dopa decarboxylase

Question 29

Generic of Mirapex?

Answer 29

Pramipexole

Question 30

Generic of Sinemet?

Answer 30

Carbidopa/Levodopa

Question 31

Generic of Requip?

Answer 31

Ropinirole

Question 32

What are the COMT inhibitors?

Answer 32

Entacapone

Question 33

What are the dopamine agonists?

Answer 33

Pramipexole + Ropinirole

Question 34

How is entacapone dosed?

Answer 34

200mg for every dose of carbidopa/levodopa

Question 35

How is Alzheimer's disease treated?

Answer 35

Mild - ACh inhibitors (donepezil, rivastigmine, galantamine) Severe - ACh inhibitors and/or memantine

Question 36

Generic of exelon?

Answer 36

Rivastigmine

Question 37

Generic of Aricept?

Answer 37

Donepezil

Question 38

Generic of Lamictal?

Answer 38

Lamotrigine

Question 39

What causes seizures?

Answer 39

Imbalance of inhibitory GABA and excitatory Glutamate

Question 40

Generic of Topamax?

Answer 40

Topiramate

Question 41

Generic of Depakote?

Answer 41

Divalproex

Question 42

Therapeutic range of carbamazepine?

Answer 42

4 - 12

Question 43

What kind of testings is required for carbamazepine?

Answer 43

HLA-B*1502

Question 44

Generic of Trileptal?

Answer 44

Oxcarbazepine

Question 45

Generic of Tegretol?

Answer 45

Carbamazepine

Question 46

Valproic acid therapeutic range?

Answer 46

50-100

Question 47

BBW for divalproex/valproate?

Answer 47

Hepatotoxicity, teratogenic

Question 48

Which anti-epileptic drug is associated with hyponatremia?

Answer 48

Carbamazepine/Oxcarbazepine

Question 49

Phenytoin/Fosphenytoin are strong (inducers/inhibitors) of enzymes, what does that mean?

Answer 49

Strong inducers - decrease the concentration of many drugs

Question 50

Which AED is an autoinducer?

Answer 50

Carbamazepine

Question 51

Valproic acid + Lamotrigine, what happens?

Answer 51

Valproic acid will increase concentration of lamotrigine Most other AED will decrease levels of lamotrigine

Question 52

What kind of mineral deficiency do all AED cause?

Answer 52

Calcium + Vit. D