Psych/Neuro Flashcards

(66 cards)

1
Q

investigations when possible diagnosis of Autism

A
  • school observation
  • ADI-R
  • ADOS-2
  • DISCO
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2
Q

what 3 functional domains does the ADI-R focus on

A
  • language and communication
  • reciprocal social interactions
  • restricted, repetitive and stereotyped behaviours and interests
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3
Q

DISCO stands for

A

diagnostic interview for social and communication disorders

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4
Q

MRI scan findings in those with autism

A

brain enlargement - especially in occipital, parietal and temporal lobes;

could be due to neuronal death, increased neurogenesis or even increased production of glial cells or vasculature

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5
Q

what does Sally-Anne test assess

A

theory of mind

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6
Q

licensed pharmacological treatment for aggressive behaviour in children

A

Risperidone

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7
Q

psychotherapy for both parents and autistic patient

A
  • CBT
  • behavioural management programmes
  • TEACCH
  • Educational psychology
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8
Q

medications used as adjuncts for ASD to psychological interventions

A

SSRI

Risperidone antipsychotic

Melatonin - help to reduce sleep latency

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9
Q

how is pain illicit in a child for GCS assessment

A

pressing hand on supra-orbital notch; beneath the end of the eyebrow with thumb

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10
Q

differentials for a 2 year old with seizures

A
  • febrile convulsion
  • epilepsy
  • encephalitis/meningitis
  • sepsis
  • brain tumour
  • metabolic disorders
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11
Q

immediate management of seizure

A

ABC assessment
High flow oxygen
blood glucose measurement

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12
Q

management of status epilepticus

A
  • High flow oxygen, ABC, Bm
  • Midazolam
  • Lorazepam
  • Phenytoin (over 20 mins)
  • RSI with thiopentone (if seizure has lasted longer than 30 mins)
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13
Q

when to do RSI with theopentone for status epilepticus

A

seizure lasting longer than 30 minutes

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14
Q

how long does a simple febrile seizure last

A

< 15 mins

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15
Q

differences between simple and complex febrile seizures

A

simple

  • last less than 15 mins
  • resolve within 24 hours
  • no neurological deficits
  • fever present
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16
Q

following what seizure may a Tods palsy occur
and
what is a Tods palsy

A

following a complex febrile seizure

Tods palsy = focal weakness in part or all of body following a seizure and usually subsides after 48 hours

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17
Q

3 indications for an urgent CT head/MRI

A
  • encephalitis/coma
  • suspected raised ICP
  • progressive neurological deficit
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18
Q

indications for elective MRI

A
  • child < 2 years
  • focal neurological deficits
  • focal epilepsy
  • assoc. learning difficulties
  • epilepsy resistant to full doses of appropriate drugs
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19
Q

when to do an elective EEG

A
  • development of language regression

- strong suspicion of epilepsy

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20
Q

definition of epilepsy

A

recurrent transient paroxysmal attacks of disturbed consciousness and sensorimotor function resulting from abnormal electrophysiological discharges of cerebral neurones

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21
Q

5 types of generalised seizures

A
  • tonic clonic
  • absene/petit mal
  • myoclonic
  • tonic
  • atonic/akinetic
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22
Q

feature of a partial seizure

A

aura = describes the effects of initial focal electrical events e.g. unusual smell, tingling in a limb, strange inner feeling

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23
Q

types of partial seizures

A
  • simple partial

- complex partial

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24
Q

what does early hand preference before 12 months indicate a higher risk of

A

higher risk of hemiplegia on non dominant side

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25
causes of delayed walking
- duchennes - spina bifida - developmental dysplasia of hip - rickets - cerebral palsy
26
name for the life long condition that affects movement and coordination caused by a problem with the brain that occurs before, during or soon after a birth
cerebral palsy
27
symptoms of cerebral palsy
- delay in reading developmental milestones - too stiff/too floppy - weak arms/legs - fidgety/clumsy - waling on tip toes - swallowing and learning difficulties
28
causes of cerebral palsy
- bleeding into brain - decreased oxygen supply to brain - meningitis - brain injury - damaged brain during or soon after birth
29
MRI finding in cerebral palsy
periventricular leucomalacia
30
typical presentation of cerebral palsy
- poor feeding - floppy at birth/hypotonia - fits in a neonate - delayed meeting developmental milestones
31
4 common presentations of cerebral palsy
- hemiplegia - diplegia - quadriplegic - dyskinetic
32
features of scissoring gait in cerebral palsy
- talipes equinovarus deformity - adduction of hips with scissoring - plantar flexion of feet - inward pointing knees - assoc. rotation and swaying of trunk - tip toeing
33
charity for supporting cerebral palsy
scope
34
what is scope and what does it offer?
charity for cerebral palsy offers - support info for families - support groups - online community
35
chemical that is - neurotoxic - high levels can result in respiratory signs
ammonia
36
2 types of inborn errors of metabolism
- urea cycle disorders | - organic acidaemias
37
features of urea cycle disorder
- high ammonia - liver dysfunction - metabolic alkalosis
38
acid base imbalance caused by urea cycle disorders
metabolic alkalosis due to high ammonia acting as a respiratory stimulant
39
acid base imbalance from organic acidaemias
mixed metabolic acidosis + high ammonia
40
ammonia scavenging medications
- Na benzoate | - Na Phenylbutyrate
41
what is metabolic acidosis corrected by
IV Na Bicarb
42
serious complication of high ammonia
mild cerebral oedema causing seizures
43
9 common conditions that the heel prick test tests for
- cystic fibrosis - MSUD - sickle cell - hypothyroidism - PKU - MCAD - homocystinuria - isovolemic acidaemia - glutamic aciduria
44
treatment of PKU
phenylalanine free diet, supervised by specialist dietician and paediatrician
45
standardised questionnaire to assess for ADHD
Conner's rating scale
46
protective factors for cerebral palsy
- Mg Sulfate - abx - corticosteroids
47
what is periventricular leukomalacia
cystic changes occuring in the periventricular white matter; caused by infection/inflammation resulting in prematurity and MRI change
48
global developmental delay
significant delay in milestones in 2 or more areas (more/=2 SD below the mean)
49
risk factors for cerebral palsy
- prematurity - intrauterine infections - birth asphyxia - meningitis - CP arrest
50
what is ataxic gait characterised by
shaky movements, imbalances, caused by cerebellar damage
51
what is spastic gait characterised by
muscles appear tight and stiff... due to damage to motor cortex
52
what is dyskinetic gait characterised by
involuntary movements; due to damage to basal ganglia
53
most common type of cerebral palsy
spastic
54
3 medx to manage hypertonia
- baclofen - diazepam - botulinum toxin
55
3 key features of autism
- communication difficulties - social interaction difficulties - inflexible thinking
56
cause of autism
- unknown - positive fhx - assoc. with other medx conditions
57
what is CAHMS role in autism
helping families understand their child and put in strategies to cope with their behaviour
58
3 features of ADHD
- inattention - hyperactivity - impulsivity
59
cause of ADHD
- genetic factors - head injury - prematurity - low birth weight
60
duration of symptoms for a diagnosis of ADHD
6 symptoms of inattention + 6 symptoms of hyperactivity present in 2 situations for more than 6 months
61
who does the ADHD assessment
- psychiatrist - paediatrician - social worker - learning disability specialist
62
rating scale for ADHD
conners scale
63
charities that support ADHD
Young minds | ADDiss
64
CNS stimulants for ADHD treatment
- Methylphenidate | - Dexamphetamine
65
side effects of Methylphenidate
- abdo pain - insomnia - headaches - weight loss
66
non pharmacological treatments for ADHD
- behavioural interventions: star charts + focused praise, - organisational skills - time management - anger + stress management - attention deficit disorder information + support service