Psychiatry Flashcards
(207 cards)
What is somatic syndrome?
Depression with more physical symptoms
What is atypical depression?
Mood reactivity
Increase appetite and sleep
Leaden paralysis (heavy limbs)
What is psychotic depression?
Paranoid or hypochondriae or with nihilistic delusions
What are nihilistic delusions?
A nihilistic delusion of the nonexistence or dissolution of a body part; in extreme form, the delusion of being dead or nonexistent
Rate of suicidal thoughts/behaviour in depression?
25%
Onset age of bipolar disorder?
Late teens/early 20s
Bipolar disorder is a spectrum of..? (2 things)
Severity (mania vs hypomania)
Proportion (more depressed/manic)
Symptoms of hypomania + mania?
Elevated mood Restlessness Increased talkativeness (pressure of speech) Decreased need for sleep Increased sexual energy Difficulties concentrating
Symptoms of mania?
Flight of ideas
Loss of social inhibitions
Grandiosity
Reckless behaviour
Bipolar carries increased risk of … compared to other mental disorders
Suicide
Which kind of antidepressants are generally first line?
SSRIs
How long should antidepressants be used?
At least 6 months after remission
Treatment for bipolar in acute mania?
Anti-psychotics + Lithium
Benzodiazepines for symptom control
Hospitalisation if severe
Treatment of bipolar depressive phase?
Anti-depressant (SSRI- fluoxetine, lamotrigine)
+ Lithium
ECT if severe
What should be monitored in elderly people taking anti-depressants?
Sodium- risk of hyponatraemia
What do monoamine oxidase inhibitors (MAOIs) do?
Inhibit enzyme responsible for monoamine metabolism (less serotonin/noradrenaline metabolised)
Examples of MAOIs?
Moclobemide (reversible)
Phenelzine (irreversible)
When put fennel in food, it’s irreversible!
Side effects of MAOIs?
Postural hypotension Drowsiness Nausea Insomnia Constipation Peripheral Oedema
Depersonalisation?
Body not yours or disconnected from you
Derealisation?
Disconnected from world or “spaced out”
What are the dietary restrictions associated with MAOIs?
Tyramine foods (cheese, red wine, red meats etc)–> cause hypertensive crisis
How do tricyclic antidepressants work?
Block the reuptake of monoamines (5-HT and noradrenaline) at the presynaptic terminals
Examples of tricyclics?
amitriptyline, imipramine, dosulepin, lofepramine
When should tricyclics be avoided?
In suicidal patients