Psychiatry buzzwords Flashcards

(34 cards)

1
Q

Third person auditory hallucinations

A

Schizphrenia

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2
Q

Mesocortical dopamine hypoactivity

A

Negative and cognitive symptomsinschizophrenia

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3
Q

Subcortical dopamine hyperactivity causes…

A

Psychosis

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4
Q

What is thetuberofundibular pathway in the brain concerned with?

A

Prolacin release

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5
Q

What is the nigrostriatal tract concerned with?

A

Extra-pyramidal motor movements

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6
Q

What is the mesolimic system invloved in?

A

Motivation & reward

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7
Q

What is the mesolimbic pathway dysregulated in?

A

Schizophrenia

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8
Q

How does Da blockade compare to Da agonism in terms of clinical pressentation?

A

Da blockade - Depression

Da agonism - psychosis

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9
Q

Side effects of clozapine

A

Agranulocyosis
Cardiomyocitis
Weight gain

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10
Q

Which of the atypical anti-psychotics causes the most weight gain?

A

Olanzapine

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11
Q

When is clozapine indicated?

A

When have been tried on 2 other anti-psychotics and need to be a consultant to prescribe

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12
Q

How is clozapine monitored?

A

Once a week for 6 months

Then once every 2 weeks fro 6 months then every 4 weeks thereafter and a month after discontinuation

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13
Q

What are the functions of the limbic system?

A

M2 - Memory, Motivation
O- Olfaction
V - Visceral afferents
E - Emotion

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14
Q

What are the brain changes in schizophrenia?

A

Reduced frontal lobe volume (and grey matter)
Enlarged lateral ventricles
Reduced grey matter in the temporal cortex

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15
Q

What is pressure of thought

A

Varied ideas in abundance (characteristic of mania but also seen in schizophrenia)

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16
Q

What is poverty of thought?

A

Patient reports lack/absence of thoughts

17
Q

What is thought blocking?

A

Abrupt and complete interruption of stream (strongly associated with schizophrenia)

18
Q

What is flight of ideas?

A

Quickly moving from one topic to anoher but there is a link unlike knights move thinking

19
Q

What is knights move rhinking?

A

Quicly moving fromonetopic to another whenthere doesn’tseemtobealink

20
Q

When is knights move thinking seen?

A

Inbipolar during mania

21
Q

How are EP side effects treated?

22
Q

WHat is the role of the amygdala?

A

Involved in normal response to threat

23
Q

What is the relationshipp between the PFC and the amygdala?

A

PFC dampens down amygdala response to threat

24
Q

What s the steps of management of OCD?

A
  1. SSRI
  2. SSRI
  3. TCA or SSRI
25
What TCA is used in OCD?
Clomipramine
26
What are the cut off's forlearning diabilities?
``` 70-80 = borderline 50-69 = mild 35-49 = moderate 20-34 = severe <20 = profound ```
27
What is Becks triad?
Negaive feelings about self, world & future
28
What symptoms do NMDA antagonists produce?
Psychotic symptoms
29
What should be used to treat alcohol withdrawal?
Chlordiazepoxide
30
When would alcohol withdrawal seizures occur?
Within 48 hours
31
When would delirium tremens occur?
Between 48 and 72 hours
32
What can MAO inhibitors react with to cause hypertensive crisis?
``` Tyramine containing foods Ephridine Nasal decongestants TCAs Pethidine ```
33
How is hypertensive crisis caused by MAO inhibitors treated?
Phentolamine infusion
34
When should TCAs be avoided?
Cardiac problems or patients with suicidal intent