Psychiatry Drugs

Question 0

What is the benzodiazepine used in alcohol withdrawal?

Answer 0

Chlordiazepoxide

Question 1

What is the fastest acting benzodiazepine?

How quick does this act?

Answer 1

Lorazepam
Orally 1 hour
IM 30 mins

Question 2

What is the trade name for diazepam?

Answer 2

Valium

Question 3

What neurotransmitter do benzodiazepines affect?

Do they enhance or inhibit?

Answer 3

GABA

Enhance it’s affect?

Question 4

What are the therapeutic properties of benzodiazepines?

Answer 4

Sedative 
Anxiolytic
Hypnotic (sleep inducing)
Muscle relaxant 
Anticonvulsant

Question 5

In a rapid tranquilization how much lorazepam would you give?

How much haloperidol?

Answer 5

1mg lorazepam

5mg haloperidol

Question 6

What are the risks with taking benzodiazepines?

Answer 6

Respiratory depression

Hypotension

Question 7

What are the general side effects of antipsychotics?

Answer 7

EPSE
Weight gain
Hyperprolactinaemia
Anti cholinergics
Postural hypertension 
Diabetes

Question 8

How do atypical antipsychotics work?

Answer 8

Antagonise the dopamine pathways

Question 9

How doss aripiprazole work?

Answer 9

dopamine parties agonist so has a different effect in meso cortical and mesolimbic areas

Question 10

In schizophrenia what is the general management?

Answer 10

Orlanzepine (atypical)
Then 
Zuclopenthioxol
Then
 Clozapine
Then augment clozapine

Question 11

Max does of Orlanzepine?

And starting dose?

Answer 11

20 mg

Start on 5mg

Question 12

Starting dose of clozapine?

Max dose?

Answer 12

12.5mg

Up to 200mg

Question 13

How long does it take to titration clozapine up to its full dose?

Answer 13

2 weeks

Question 14

If you miss a dose of clozapine what must happen?

Answer 14

Restart titration at 12.5mg

Question 15

Name 3 atypical antipsychotics

Answer 15

Orlanzapine 
Quetiapine
Rispiridone
Aripiprazole
Amisulpride
Zotepine

Question 16

Name 3 typical antipsychotics?

Answer 16

Haloperidol
Fluphenazine
Chloepromazine
Promazine

Question 17

Worst antipsychotic for increasing prolactin?

Answer 17

Rispiridone

Question 18

What are the symptoms of neuroleptic malignant syndrome?

Answer 18

Autonomic dysfuction
- temp /HR / BP
Confusion
Ataxic
High CK

Question 19

What drugs give the risk of neuroleptic malignant syndrome?

Answer 19

Antipsychotics

Question 20

What drugs cause anti cholinergics side effects?

Answer 20

Antipsychotics
Tricyclic
SNRI (venlefaxine, juloxcitine)

Question 21

What is the safest antidepressant after an MI?

Answer 21

Sertraline

Question 22

What SSRI is worse for affecting QTc interval?

Answer 22

Citalopram

Question 23

What is a normal QTc?

Answer 23

Less than 450

Question 24

Which SSRI is best for a non compliment patient?

Answer 24

Fluoxetine

Question 25

Tricyclic antidepressants can cases weight gain, what neurotransmitter is thought to cause this?/

Answer 25

Histamine

Question 26

What are the side effects of TCA?

Answer 26

Anticholinergic Postural hypotension Weight gain Sedation

Question 27

Apart from depression what can fluoxetine be used for?

Answer 27

OCD | Bulimia nervosa

Question 28

Max dose of fluoxetine?

Answer 28

60mg

Question 29

Which Antidepressant is more associated with hyponatraemia?

Answer 29

SSRIs

Question 30

What drug type is imipramine and lofepramine?

Answer 30

Tricyclics

Question 31

What drug type is dosuleptin?

Answer 31

Tricyclics

Question 32

Anticholinergic drugs inhibit what type of nerve impulses?

Answer 32

Parasympathetic

Question 33

What drugs cane be given to manage EPSEs?

Answer 33

Anticholinergics

Question 34

What drugs can be given to manage akathesia?

Answer 34

Beta blockers

Question 35

What type of EPSE are oculogyric crisis and torticollis?

Answer 35

Acute dystonia

Question 36

What is torticollis?

Answer 36

Twisted neck