Psychopharm Flashcards
(60 cards)
produce similar effects to those produced by an NT
agonist
produce similar (but less than) effects to those produced by an NT or agonist
partial agonist
produce no activity in a cell on their own, but instead, reduce or block the effects of an NT or agonist
antagonist
exert their effects by mimicking the effect of an NT at a receptor site
direct agonist
attach to a binding site on a receptor cell (other than the ones used by the NT) and interferes with the action of the NT
indirect antagonist
attaches to a binding site on a receptor cell (other than the ones used by the NT) and facilitates the action of the NT
indirect agonist
exert their effects by attaching to a NT’s receptor site and interfering with action of the NT
direct antagonist
produce an effect opposite the effect of the NT or agonist
inverse agonist
the ____ culture is a poorer metabolizer of certain isoenzymes
asian
the most serious extrapyramidal effect is
tardive dyskinesia
_____, the most potent antipsychotic, is associated with the most severe ______ effects
haloperidol, extrapyramidal
a potentially fatal side effect of antipsychotics is
neuroleptic malignant syndrome
atypical antipsychotics can produce _____l which is a marked decrease in white blood cells
agranulocytosis
TCAs block the reuptake of :
norepinephrine, serotonin,and/or dopamine
one huge issue with TCAs is that they can be ____, which results in numerous cardiovascular symptoms
cardiotoxic
SSRIs are less _______ than TCAs and less likely to result in _____ impairment
cardiotoxic, cognitive
Administration of an SSRI with an MAOI can result in _____, which is potentially fatal
serotonin syndrome
the most dangerous side effect of MAOIs is ______ crisis
hypertensive crisis
aged cheeses, beer, red wine, meats, banana, avocado, should not be eaten if being prescrbed
MAOI
a well known NDRI
buproprion (wellbutrin)
a well known SNRI
venlafaxine (effexor)
although they are in the same class _______, combining an anxiolytic with ____ or a _____ can be deadly because of their superadditive nature
sedative-hypnotics…..alcohol, barbiturate
sedative-hypnotics also produce _________, which means that when tolerance develops to one it is likely to be shown for others as well
cross-tolerance
what would be used to treat angina, migraines, glaucoma
beta blockers
