Psychotherapeutics Flashcards
(20 cards)
What is the pathophysiology behind extrapyramidal side effects?
Dopamine receptor antagonism in the nigrostriatal pathway
How is chlorpromazine classed?
Antipsychotic
What is dystonia?
Involuntary sustained muscle contractions of the face, neck, jaw or back
What is pseudo-parkinsonism?
Tremors and bradykinesia
What is akathisia?
Physical restlessness and anxiety
What is dyskinesia?
Involuntary repetitive movements like lip smacking, tongue darting, chewing movements, rapid blinking
What is clonazepam?
A benzodiazepine used to treat anxiety
What is citalopram and how does it work?
An antidepressant that works by inhibiting the re-uptake of serotonin
What is lorazepam used for?
To treat anxiety disorders and promote sleep / sedation
Which class of antidepressants react poorly with tyrannie or dopamine containing foods?
MAO inhibitors
What is serotonin syndrome?
A life-threatening condition that results from increased CNS serotonergic activity
How does the antipsychotic olanzapine work?
It selectively blocks dopamine receptors
How does the antidepressant Duloxetine work?
It inhibits the reuptake of serotonin & norepinephrine in the CNS
How is Temazepam classified?
It is a benzodiazepine
How is chlordiazepoxide classified?
It is a benzodiazepine
How is Risperidone classified?
It is a 2nd generation antipsychotic
How does Risperidone work?
It inhibits the D2 dopaminergic receptors and 5-HT2A serotonergic receptors in the brain
How is Citalopram classified?
It is a selective serotonin reuptake inhibitor
What is Lorazepam’s mechanism of action?
It increases the frequency of opening of chloride ion channels in neurons to cause hyperpolarization
What is Phenobarbitol’s mechanism of action?
It increases the duration of opening of chloride ion channels in neurons to cause hyperpolarization
