Pulm phys Flashcards

(48 cards)

1
Q

what is flow proportional to

A

pressure gradient and inversly to radius

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2
Q

What is V0

A

dead space air

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3
Q

what is Va

A

air in aveoli

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4
Q

explain the beta agonists impact on beta 2

A

when NE binds- cascade of events leading to smooth muscle relaxation
-when we use beta agonist, radius increases and requires less pressure to get air flow

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5
Q

talk about cross sectional area

A

as cross sectional area increases, velocity slows down. velocity of air flow slow in alevoli which allow gas exhcnage to occur

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6
Q

what is ficks law of diffiusion

A
  • looking at efficacy of gas exchange

ex: pt w pulm fib: tissue thickness= greater so diffiusion limited ability to exhchange O2 and Co2 is decreased

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7
Q

what is pH directly related to

A
  • bicarbonate
  • more bicarb could raise pH
  • more co2 in body=more protons being released
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8
Q

do people with COPD retain co2?

A

yes which causes pH to fall

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9
Q

what is the conducting portion of the respiratory system

A
  • “conditions” the inspired air
  • bulk transport of air
  • upper airway important for conditioning bc it warms air, filters large particles and saturates air with water vapor
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10
Q

what is the respiratory portion of the respiratory system

A
  • gas exchange function
  • everything conducting until respiratory bronchiole
  • dead space: air flow but no gas exchange
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11
Q

where does the majority of gas exchange occur

A

alevolar sac and ducts

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12
Q

what is ventilation

A

the process by which air moves into and out of the lunges

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13
Q

how and why does ventilation occur

A
  • pressure gradients move air: all you need is a small amount to allow for air flow to occur
  • musculoskeletal pump allows this to occur
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14
Q

what is hyperventilation

A

blowing off co2

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15
Q

what is hypoventilation

A

retaining co2

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16
Q

does the entire “inspired” breath contribute to gas exhcange?

A

no.

-there is dead space

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17
Q

does the entire tidal volume contribute to gas exhcange

A

no

-thats why we have dead space and alevolar ventilation

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18
Q

what is the diff between hypoxia, hypoxemia and ischemia?

A

hypoxemia: low amount of o2 in blood
hypoxia: at tissue level
ischemia: lack of blood flow

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19
Q

what does the pulse ox on a finger measure

A

hypoxemia

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20
Q

explain dead space estimated by BW

A

if you took a breath thats the same amount as BW…not much gas exhcange would occur bc not overcoming dead space
-next to no alveolar ventilation
air will become 100% co2

21
Q

does air go evenly through the lung when you take a breath?

22
Q

talk about alveoli at rest

A

at rest, some are collapsed/not contributing to gas exhcnage

with exercise, they will participate=phyisiologic deadspace

23
Q

what is minute ventilation

A

amount of air exhaled in one minute

24
Q

what are the two componenets of ventilation

A

physiologic dead space: wasted ventilation

alveolar ventilation: gas exchange

25
where does a majority of air go when you take a deep breath
base of lung
26
is ventilation evenly distributed
no
27
what happens as lung compliance goes up?
they become less stiff
28
what are the non-elastic factors of breathing
- gas flow | - airway resistnace
29
what is surfactant produced by
type II pneumocytes
30
what does surfactant do
- lessens surface tension to decrease muscular effort needed to ventilate the lungs - prevents collapse of small alveoli especially during expiration - immune effect to protect the lungs against invaders
31
how do bonds break?
surfactant gets in between and breaks them which lessens surface tension and increases compliance
32
what is surfactant made of
- lipids and proteins | - both hydrophilic and hydrophoibc
33
where does most volume change occur?
- bottom of lung when we take a deep breath | - top already maximally expanded: cant add more air
34
what happens as we take a deep breath?
lungs get stiffer
35
what are the factors that impact air flow and resistance
``` Q=P/R -resistance: radius airway length gas viscosity lung volume ```
36
what does sympathetic stimulation cause?
bronchodilation
37
what is WOB
work of breathing -work of respiratory muscles to overcome elastic and resistnace factors from the airways, lungs, chest wall to expand the chest and lungs things that will increase work: - reduced lung compliance - higher RR - deeper breathing elastic factors: compliance of lungs, chest wall and abs airway resistance: bronchospasm, airway inflammation, swelling and secretions
38
what is acinus
the functional gas exchange unit consists of: -respiratory bronchioles -alveolar ducts, alevolar sacs, and alevoli
39
what are type I pneumocytes?
-very thin 95% alveolar surface area -gas exhcnage
40
what are type II pneumocytes?
- synthesize and secrete surfactant - reduce surface tension - allow alveoli to remain open
41
what creates a pressure gradient?
MSK pump & coordination interaction of respiratory muscles | -rib cage and lungs
42
what is breathing efficacy?
related to depth of breathing
43
what happens if a patient is not overcoming their dead space?
more CO2 being kept inside
44
what is the order of gas distribution in the lung?
most to least | bottom> middle> middle lobe> top lobe
45
what is the primary factor in gas distribution in the lung?
compliance
46
which part of the lung has low compliance?
top
47
do people with obstruction have a high or low compliance?
high
48
do people with restrictions have a high or low compliance?
low