Pulmonary Flashcards
(210 cards)
what is atopy
wheezing, eczema, and seasonal rhinitis
what is the pathophysiology of ASTHMA
it is an overproduction of IGE which results in there beta 2 receptors.
This leads to inflammation and mucus production and bronchial smooth muscle contraction
Clinical features of asthma
FEV1/FVC
what is bronchitis
infection and inflammation of the bronchial tree
there is also mucous formation
what is the most common cause of bronchitis
80% viral
who is at risk of acute bronchitis
smokers, COPD, DM and immunocompromised
what test should you order for acute bronchitis and why
cxr to rule out pneumonia
how do you treat acute bronchitis
albuterol and an antitussive and hydration
what is the most common infection with cystic fibrosis
pseudomonas
what is the etiology of COPD
smoking
it can also be due to alpha 1 antitrypsin
what pattern is seen on PFT in a patient with COPD
FEV1
what is the pattern for PFT in a patient with restrictive pattern
FEV1 is normal or slight decreased
FVC decreased more than FEV1
FEV1/FVC ratio is increased
TLC is decreased
people with emphysema are know as
pink puffers
they are thin due to increased energy expenditure during breathing
patient tend to lean forward
Patients have a barrel chest increased AP diameter
accessory muscle use
people with chronic bronchitis are know as
blue bloaters
they are over weight and cyanotic due to hypercapnia and hypoxemia
chronic cough and sputum production
what is bronchiectasis
irreversible dilation of the airways due to inflammatory destruction of the airway walls
Secondary infection with Pseudomonas aeruginosa
etiology of bronchiectasis
Cystic fibrosis most common Mechanical obstruction, tumor, mucus Infectious, TB, Pneumonia, MAC hypogammaglobulinemia Chronic aspiration
signs and symptoms of bronchiectasis
chronic cough mucopurulent sputum (foul smelling)
hemoptysis due to rupture of blood vessels near bronchial walls
wheezing
digital clubbing
recurrent or persistent pneumonia
how is bronchiectasis diagnosed?
High rest CT
PFT shows obstructive pattern
CXR is normal in most cases
what is the treatment for bronchiectasis?
Abx for acute exacerbations Bronchial hygiene hydration chest PT Bronchodilators
what is Cystic Fibrosis
defect in chloride channel protein causes impaired chloride and water transport which leads to thick viscous secretions in the respiratory tract, exocrine pancreas, sweat glands, intestines and GU
who is affected by CF
autosomal recessive condition predominantly affecting caucasians
what happens with patients who have CF
typically get obstructive lung disease with chronic pulmonart infections (pseudomnonas), pancreatic insufficiency and other GI problems
what is the treatment for CF
pancreatic enzyme replacement, fat soluble vitamins, chest PT, vaccinations for influenza and pneumococcal and ABX for infections
what is emphysema
permanent enlargement of air spaces distal to terminal terminal bronchioles due to destruction of alveolar walls from protease.
Elastase is released from PMN and macrophages and digest human lung. This is inhibited by alpha1-antitrypsin