PULMONARY Flashcards

(49 cards)

1
Q
tactile fremitus and percussion findings for:
1 consolidation/pna
2 pleural effusion
3 pneuothorax
4 emphysema
5 atelectasis
A
1 increased TF, dull to P
2 decreased TF, dull to P
3 decreased TF, hyperresonant to P
4 same as 3
5 decreased TF, dull to P
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2
Q

best initial test for acute asthma exxacerbation?

most accurate?

A

peak expiratory flow or ABG

most accurate = PFTs (decreased FEV1/FVC ratio)

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3
Q

if asx, best test to evaluate asthma is

A

methacholine challenge (20% decrease in FEV1)

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4
Q

if asthma, PFT will show an increase of ____ in response to albuterol

A

> 12%

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5
Q

stepwise asthma treatment

6 steps

A

1 inhaled SABA (albuterol)
2 low dose ICS (beclomathasone, budenoside, fluticasone) OR cromolyn/theophylline/leukotriene mods
3 add LABA (salmeterol, formeterol) OR increase ICS
4 increase ICS to maximum and cont LABA + SABA
5 add omalizumab
6 oral corticosteroids (prednisone)

**never use LABA first or alone

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6
Q

tx of acute asthma attack

A

oxygen
albuterol
steroids

if they dont respnd, intubate

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7
Q

young patient and nonsmoker who has air trapping and copd picture. think

A

alpha 1 antitrypsin deficiency

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8
Q

best initial test for copd is

most accurate?

A

cxr
look for increased ap diameter and flattened diaphragm/air trapping

most accurate is PFTs = FEV1 and FVC decreased, FEV1/FVC <70%, increased TLC, incomplete improvement with albuterol (not reversible)

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9
Q

copd treatment

1) things that improve mortality and delay progression
2) improves sx but no change in progression or mortality
3) no benefit

A

1 - smoking cessation, oxygen therapy, and flu/pneumococcal vaccines

2 - albuterol (SABA), anticholinergics (ipratropium, tipropium), steroids, LABA (salmeterol), and pulmonary rehab

3 cromolyn, leukotriene mods (monteleukast)

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10
Q

criteria for oxygen use in copd

A

pO2 below 55 or ox sat below 88%
OR
signs of right sided heart failure or elevated hematocrit with pO2 <60 or sat <90%

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11
Q

cxr for bronchiectasis

most accurate test?

A

thickened dilated bronchi, tram tracks

most accurate test is high res CT

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12
Q

allergic bronchopulmonary aspergillosis
mech?
dx?
tx?

A

hypersensitivity of the lungs to fungal antigens (patient with asthma and atopy)

brown flecked sputum and infiltrates on cxr

dx: peripheral eosinophilia, skin test reactivity to aspergillus ag, serum IgE elevated, CXR/CT infiltrates

tx: oral prednisone (inhaled DOES not work for ABPA)
+ itraconazole orally for recurrent cases

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13
Q

most accurate test for CF is

A

increased sweat chloride test (cl>60)

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14
Q

CF treatment

A

routine abx (inhaled aminoglycosides)
recombinant human deoxyribonuclease
bronchodilators (albuterol)
vaccinations (pneumococcal and influenza)

lung transplant when unresponsive to above therapy

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15
Q

CAP is defined as

A

pna occuring before hospitalization or within 48 hours of admission

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16
Q

what organism is associated with CAP with reference t contaminated water or ventilation?

A

legionella

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17
Q

pneumonia presentations:
1 hemoptysis and currant jelly sputum
2 foul sputum “rotten eggs”
3 dry cough, rarely severe, bullous myringitis
4 GI upset (n/v, diarrhea) or CNS (ha/confusion)
5 AIDS with <200 cd4

A
1 klebsiella
2 anaerobes
3 mycoplasma pneumoniae
4 legionella
5 pneumocytis (PCP)
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18
Q

best initial test (but not most accurate) for pna?

A

cxr

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19
Q

4 pneumonia orgs not visible on gram stain

A

coxiella
chlamydia
legionella
mycoplasma

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20
Q

sputum gram stain is “adequate” if ….

A

there are more than 25 white blood cells and less than 10 epithelial cells

21
Q

how to diagnose legionella?

A

urine antigen
or
culture on charcoal yeast agar

22
Q

outpatient vs inpatient tx for CAP

A

outpatient is macrolide (azithromycin or clarithromycin) or doxycycline
—if comorbidities do resp fluoroquinolone (levo or moxi)

inpatient is levo or moxi OR ceftriaxone + azithromycin

23
Q

exudate/empyema is suggested by what labs

A

LDH >60% of serum
protein >50% of serum
pH <7.2

24
Q

do healthcare workers need pneumococcal vaccine?

25
every 65+ should receive the ___ followed by ___ 6-12 months later
pcv13 23pneumococcal
26
health care associated pneumonia defined as
pna developing more than 48 hours after admission or after hospitalization in past 90 days often gram - (e coli or pseudomonas)
27
treatment for healthcare associated pna
NOT macrolines (azithro) need to treat for gram - bacilli use: antipseudomonals cefepime or ceftazidine OR pip/tazo OR imipenem/meropenem
28
tx for ventilator associated pna
``` 3 drug therapy antipseudomonal beta lactam (piptazo, ceftazidime) + aminoglycoside or fluoroquinolone + vanc or linezolid ```
29
most accurate test for PCP is when to do it?
BAL if sputum stain is negative in an aids patient (if sputum is +, no need to do the BAL) also if LDH is normal, it cant be PCP!
30
ppx for PCP? tx? if cant tolerate ?
both are tmp-smx add steroids if pO2 <70 or A-agradient >35 tmp smx can cause rash/bone marrow suppression....can change to clinda + primaquine OR pentamidine choose pentamidine if patient has G6PD
31
tb treatment
RIPE for 2 months..then just RI for 4 more
32
patient with abnrmal CXR or symptoms suggestive of tb should get what next done?
sputum acid fast testing x3
33
if screening ppdis + and cxr -, tx?
9 months isoniazid + pyridoxine
34
best initial step in all lung lesions/nodules is... if it is enlarging...
compare to old cxr biopsy it
35
cryoglobulinemia is associated with hx of what disease? presentation?
hep C palpable purpura + hepatosplenomegaly + proteinuria and hematuria
36
drugs that can cause pulmonary fibrosis?
``` amiodarone bleomycin busulfan cyclophosphamide nitrofurantoin ```
37
``` types of pneumoconioses based one xposure 1 coal 2 sandblasting, mining, tunneling 3 shipyard, insulation 4 cotton 5 electronics manufacturing 6 moldy sugar cane ```
``` 1 coal workers pneumoconiosis 2 silicosis 3 asbestosis 4 byssinosis 5 berylliosis 6 bagassosis ```
38
pulmonary fibrosis presents with
loud P2 clubbing of fingers dyspnea, worse w exertion rales/crackles
39
PFTs of ILD (restrictive)
everything decreases proportionately FEV1/FVC will be normal DLCO is decreased
40
tx for ILD
prednisone
41
sarcoidosis presentation? dx? tx?
cxr showsbilateral hilar adenopathy, noncaseating granulomas, hypercalcemia (granulomas make vitamin D) cxr is best initial test LN biopsy is most accurate test PFTs will show restrictive picture (normal ratio) tx with prednisone if symptomatic
42
mc abnormality on ekg for PE
nonspecific ST-T wave changes
43
adverse effects of angiography?
allergy, renal toxicity, death
44
PE treatment
heparin bridge + warfarin (inr 2-3)
45
when is an IVC filter the tx?
cant use anticoagulation (GI or brain bleeding) recurrent emboli while on anticoagulation RV dysfunction with enlarged RV
46
when to use thrombolytics?
hemodynamically unstable acute RV dysfunction
47
If patient has HIT, switch from heparin to...
fondaparinoux
48
most accurate test for pulm htn?
right heart (swan-ganz) cath
49
who do you screen for lung cancer?
55-80 yo with 30 pack year hx, quit less than 15 years ago | annual low dose ct scan