pulmonary blood supply and gas exchange Flashcards

1
Q

what supplies lungs with oxygen

A

bronchial circulation

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2
Q

what does pulmomary circulation do broadly

A

takes C02 to lungs and picks up oxygen

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3
Q

what kind of system is pulmonary

A

high flow low pressure

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4
Q

normal arterial PO2

A

100mmHg

13.3kPa

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5
Q

normal arterial PCO2

A

40mmHg

5.4kPa

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6
Q

normal venous PO2

A

40mmHg

5.3kPa

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7
Q

normal venous PCO2

A

46mmHg

6.2kPa

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8
Q

the rate diffusion across the membrane is

A
  • directly proportional to the partial pressure gradient
  • directly proportional to gas solubility
  • directly proportional to available surface area
  • inversely proportional to thickness of membrane
  • most rapid over short distances
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9
Q

V/Q relationship at base of lung

A

blood flow is higher than ventilation as arterial pressure exceeds alveolar pressure + alveoli are compressed

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10
Q

V/Q relationship at apex of lungs

A

blood flow is less that ventilation as arterial pressure is less than alveolar pressure + arterioles are compressed

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11
Q

autoregulation when blood flow>ventilation

A

PCO2 increased and PO2 decreases. Blood moving past this area doesnt get oxygenated –> SHUNT

Inc PCO2 causes milf bronchodilation and vessels contrict to divert blood to better ventilated areas

(this only happens pulmonary circulation - in systemic there is dilation in hypoxic areas)

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12
Q

autoregulation when ventilation>blood flow

A

increase alveolar PaO2 –> pulmonary vasodilation

decrease PaCO2 –> mild bronchial constrictoin

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13
Q

shunt

A

passage of blood throigh areas of lung that are poorly ventilated

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14
Q

alveolar dead space

A

alveoli that are ventilated but not perfused

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15
Q

physiological dead space

A

alveolar DS + anatomical DS

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