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Bioquímica > Purinas > Flashcards

Purinas Flashcards

1
Q

Nucleótidos de purinas

A

Adenina (ATP) y Guanina (GTP).

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2
Q

Función de las purinas

A

Sintetizar proteínas, brindar energía en forma de ATP/GTP.

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3
Q

Enfermedades de purinas

A

GOTA, Lesch-Nydham, aguda intermitente, fenilcetonuria, diabetes, desnutrición.

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4
Q

GOTA

A

Aumento de ácido úrico.

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5
Q

Aguda intermitente (más común)

A

Se daña la enzima uro porfirina sintasa 1.

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6
Q

Lesch-Nydham

A

Daño en la enzima hipoxantina guanina fosforribosiltransferasa.

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7
Q

Fenilcetonuria

A

Aumento de la fenilalanina por daño en fenilalanina hidroxilasa.

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8
Q

Ribosa P Pirofosfato Cinasa

A

Es enzima regulada por producto.

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9
Q

Insulina en purinas

A

Es regulador hormonal.

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10
Q

Sustrato de síntesis de purinas

A

Ribosa 5 fosfato (por vía de pentosas)

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11
Q

Cofactores importantes

A

Glutamina, Formil folato, Glicina, ATP, CO2, Aspartato.

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11
Q

Producto de síntesis de purinas

A

Inosinato Monofosfato I(MP)

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Bioquímica (22 decks)

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