PWS 1

Question 1

What can students analyze in pedigrees of human families?

Answer 1

Students can analyze pedigrees to decide if a genetic disease is autosomal dominant or autosomal recessive and assign symbols to the genes and their alleles.

Question 2

What probability can students predict regarding genetic diseases?

Answer 2

Students can predict the probability of an individual within a family inheriting a genetic disease.

Question 3

What type of problems can students solve in Mendelian genetics?

Answer 3

Students can solve simple one or two gene Mendelian genetics problems and apply the χ2 test.

Question 4

What is a pedigree?

Answer 4

A pedigree is a record of the ancestry of an individual, illustrating the transmission of a heritable condition in a family.

Question 5

Phenylketonuria is controlled by a _______ allele.

Answer 5

recessive

Question 6

Affected individuals of Phenylketonuria have _______ copies of the mutant allele.

Answer 6

two

Question 7

Phenylketonuria is an example of an _______ genetic disease.

Answer 7

autosomal recessive

Question 8

What causes Phenylketonuria?

Answer 8

Phenylketonuria is caused by the alteration of the enzyme phenylalanine hydroxylase.

Question 9

What are the untreated consequences of Phenylketonuria?

Question 10

What are current methods for treating Phenylketonuria?

Question 11

Deafness is controlled by a _______ allele.

Answer 11

dominant

Question 12

How can two deaf parents have normal sons?

Question 13

Severe blistering of the feet is controlled by a _______ allele.

Answer 13

recessive

Question 14

What is the most likely explanation for the occurrence of the first affected individual in the second generation of blistering feet?

Question 15

The probability that III-1 and III-2 will have an affected child is _______.

Answer 15

1/2

Question 16

What is the chance Laura is a carrier for the rare human metabolic disease?

Question 17

What is the chance Michael is a carrier for the rare human metabolic disease?

Question 18

The chance that Laura and Michael’s first child will be affected is _______.

Answer 18

1/4

Question 19

What is the dominant trait observed in the mouse experiment?

Answer 19

grey coat color

Question 20

The albino characteristic is _______ to the grey characteristic.

Answer 20

recessive

Question 21

What are the genotypes of the parental grey mice?

Answer 21

ALB ALB

Question 22

What are the genotypes of the parental albino mice?

Answer 22

alb alb

Question 23

What is the expected ratio of grey mice to albino mice in the F2 generation?

Answer 23

3:1

Question 24

Using the χ2 test, I would _______ these results as being a chance deviation from the expected ratio.

Answer 24

accept

Question 25

What are the genotypes of the parents in Mendel's pea plant experiment?

Answer 25

RND YEL and rnd yel

Question 26

What phenotypic ratio does the Punnett Square predict in the pea plant experiment?

Answer 26

9:3:3:1

Question 27

Which ONE of the following statements is TRUE regarding flower color and seed shape?

Answer 27

The purple phenotype is dominant to the white phenotype AND the round phenotype is dominant to the wrinkled phenotype.

Question 28

What would be the genotype of the true breeding purple flowered, wrinkled seed parent?

Answer 28

COL COL ROU ROU

Question 29

What would be a suitable genotype for the F1 progeny of the flower experiment?

Answer 29

COL col ROU rou

Question 30

What phenotype ratio best describes the plants seen in the F2 generation?

Answer 30

3:1

Question 31

Using the χ2 test, I would _______ these results as being a chance deviation from the expected ratio.

Answer 31

reject