Quiz 1 Flashcards

(51 cards)

1
Q

what are the names of disorders caused by ulcers

A

dumping syndrome, zollinger Ellison syndrome

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2
Q

what does Zollinger-Ellson Syndrom

A

produces large quantities of gastrin which stimulates HCL attacks the mucosa and causes ulcers on walls on stomach

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3
Q

what is Peptic ulcer disease

A

ulcerations or erosions in mucosa and submucosa layers of the stomach, duodenum or lower esophagus

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4
Q

what is a common cause of peptic ulcer disease

A

helicobacter (H) pylori- is a bacteria that can survive in high acidity

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5
Q

what are other causes of peptic ulcer disease

A

chronic alcohol ingestion, use of NSAIDS

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6
Q

what can you use to treat peptic ulcer

A

H2 receptor blockers

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7
Q

dumping syndrome

A

caused by reduction of stomach size
hyperosmolar chime is released into the duodenum too quickly
highly acidic chyme dumped to small intestines
Fluid is drawn from blood reduces blood volume that can cause
hypertension, dizziness, nausea, abdominal pain, hypoglycemia, tachycardia
blood sugar goes up body secretes insulin cuase reduction in glucose

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8
Q

what are the parts of the small intestines

A

duodenum, jujenum, and ileum

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9
Q

what are the folds called in the small intestines and what do they do

A

Kerckring, large, circular folds of mucosa, folded into the lumen

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10
Q

villi

A

finger-like projections

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11
Q

what cells make up villi

A

enterocytes- they make up the size of the small intestines

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12
Q

microvilli

A

hair like extensions of cells plasma membranes

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13
Q

what is between the lumen and brush border

A

unstirred water layer- that is where nutrients has to cross

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14
Q

Crypts of Lieberkuhn

A

in between villi where mitosis takes place as cell # increase old cell die and fall off intestine cells are rapid turn over cell last 3-5days

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15
Q

Paneth cell

A

make antimicrobial compound, lysosome (enzyme that destroys bacteria cell wall)

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16
Q

Golblet Cell

A

secrete large amount of mucus that protect the walls of the intestines

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17
Q

all enzymes in small intestine only work at what pH

A

7-8

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18
Q

what gland get the body to specific pH and how

A

brunners gland secretes mucus and small sodium bicarbonate secretions from pancreas rich in sodium bicarbonate which is made in the duodenum

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19
Q

Regulation of intestinal motility and secretions

A

progressive contractions
segmentation contractions
neural reflexes also affected motility
migrating motility (myoelectric complex

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20
Q

neural reflexes also affect motility

A

help coordinate motility and secretions from one area to the next

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21
Q

Migrating motility (myoelectric complex)

A

series of weak contractions that sweep out intestines between meals

22
Q

what are the digestive enzymes

A

pancreatic lipase and alpha amylase

23
Q

trypsinogin is made where

24
Q

inhibitors of motility

25
bile pigments
bilirubin and biliverdin
26
the pancreas
ductless endocrine cells that secret hormones into the blood digestive enzymes produced by acinar exocrine cells pancreatic juices
27
what do the pancreatic juices contain
water electrolytes bicarbonate pancreatic digestive enzymes
28
islet of langchans produce hormones from a and b and d cells what hormones do those cells produce
the a cell produces glucagon the b cell produces vega cells which creates insulin D cells (delta cells)makes stomatostatin
29
75 percent of pancreas makes exocrine cells called
duct cells and acinar cells
30
what do duct cells do
create sodium bicarbonate
31
what do acinar cells do
secret digestive jucies
32
regulation of pancreatic secretions primary stimuli
secretin and cholecystokinin
33
secretin is stimulated aby
the s cells in proximal small intestine | responds to presence of acidic chyme
34
Cholyecystokinin is secreted by
I cells of proximal small intestine and enteric nerves and responds to presence of fat and partially digested proteins in duodenum- goes to the pancreas to release pancreatic juices
35
what state are the enzymes in the pancreas
inactive
36
what is a disorder of the pancreas
pancreatitis
37
pancreatitis
zygomens become activated and digest pancreatic tissue condidtion can occur with excessive alcohol consumption , hypertriglyceridemia, duct blockage, viral infections or injury patients often requires partially hydrolyzed nutrients or lipase
38
when to the enzymes from the pancreas become active
when it reaches the lumen
39
the liver is the
largest organ in the body and has 2 lobes made of lobules
40
liver make
hypatocytes which are made for lipid digestion
41
liver is the only organ to make
bile which is made from cholesterol
42
bile synthesis nd function
bile is composed of bile acids and salts, cholesterol, phospholipids, and bile pigments in alkaline solutions bile acts like detergent to emulsify fat
43
where is bile transported
the gallblader
44
what are the primary bile acids
cholic acid an dcenodeoxycholic acid
45
where does lipid digestion
jejunam of small intestines
46
where is secondary bile acids made
intestine
47
what are thesecondary bile acids
deoxycholic acid and lithocholic acid
48
the gallbladder does what
concentrates and store bile
49
what is a disorder of gallblader
gallstones (cholesterol crystals)
50
the recirculation and excretion of bile
most bile salts are reabsorbed-enterhypatic circulation bile moves down through ileum 90 percent is released into circulation and transported back into liver and 10 percent is excreted in large intestines
51
gallbladder undergoes contraction and
I- cells release cholecystocynase bile release through bile duct to gallbladder duct to meet common duct through sphincter of oddi