Quiz 1

Question 1

Antibodies formed by?

Answer 1

B-Lymphocytes

Question 2

Originate in bone marrow and plasma cells?

Answer 2

B-Lymphocytes

Question 3

Originate in bone marrow, mature in thymus?

Answer 3

T-Lymphocytes

Question 4

Part of passive and acquired immunity

Answer 4

T-Cells

Question 5

Fetus during pregnancy from mother via ____

Answer 5

IgG

Question 6

____ via breast milk

Answer 6

IgA

Question 7

source of histamine

Answer 7

basophils

mast cells

Question 8

defense in allergic response

Answer 8

Eosinophils

Question 9

Most numerous WBCs

Answer 9

Neutrophils

Question 10

Stimulate smooth muscle contraction (bronchospasm)?

Answer 10

Basophils

Question 11

Heavy in GI (parasites), respiratory, and urinary mucosa?

Answer 11

Eosinophils

Question 12

Release histamine, leukotrienes, cytokines, and prostaglandins

Answer 12

Basophils

Question 13

Antibodies act mainly in two ways to protect the body against invading agents:

Answer 13

(1) by direct attack on the invader

(2) by activation of the “complement system” that then has multiple means of its own for destroying the invader.

Question 14

Anaphylaxis what type of reaction?

Answer 14

Type I

Question 15

Cytotoxic (autoimmune hemolytic anemia) is what type of reaction?

Answer 15

Type II

Question 16

Immune complex disease what type of reaction?

Answer 16

Type III - Lupus, rheumatoid, glomerulonephritis

Question 17

Delayed sensitivity (contact dermatitis, graft rejection), Cell mediated - what type of reaction?

Answer 17

Type IV

Question 18

Type I hypersensitivity what Ig?

Answer 18

IgE

Question 19

Type II, III hypersensitivity what Ig?

Answer 19

IgG

Question 20

What immune reactant for Type IV?

Answer 20

T Cells

Question 21

mnemonic ACID

Answer 21

A – Allergic/Anaphylactic/Atopic(Type I);
C – Cytotoxic (Type II);
I –Immune complexdeposition (Type III);
D – Delayed (Type IV)

Question 22

Diff b/w anaphylaxis and anaphylactiod?

Answer 22

Anaphylaxis - IgE mediated

Anaphylactiod - Caused by mediator release from mast cells and basophils

Question 23

type of response for latex allergy

Answer 23

Type IV: dermatitis

Type I: anaphylaxis

Question 24

The _____ released promote ______ and macrophage migration to site.

Answer 24

DAMPs

neutrophil

Question 25

Systemic Lupus Erythmatosus (SLE) presentation? treatment?

Answer 25

Polyarthritis and dermatitis Malar rash in 1/3 of pts Renal disease in >50% Corticosteroids Antimalarial Immunosuppressant's

Question 26

What exacerbates SLE?

Answer 26

Drugs (over 80) Infection Pregnancy Surgical Stress

Question 27

Anesthesia Implications of SLE?

Answer 27

- Prone to PE, Pneumonitis, alveolar hemorrhage, and pulmonary hypertension - Restrictive disease - 1/3 of pt exhibit: Cricoarytendoid arthritis, Recurrent laryngeal nerve palsy

Question 28

Anesthetic Implications of scleroderma

Answer 28

- May require fiberoptic intubation - Bleeding with airway manipulation - Chronic hypertension - Contracted vascular volume - GERD - Hypotonis of lower esophageal sphincter - Corneal Abrasion - Prone to dry eyes - Pulmonary hypertension

Question 29

Rheumatoid Arthritis treatment?

Answer 29

Corticosteroids Methotrexate Immunosuppressant's NSAIDS