Quiz 2-Ruminants Systemic Flashcards Preview

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Flashcards in Quiz 2-Ruminants Systemic Deck (57):
1

Apthovirus from the Picornaviridae family
Whats the name of this virus?

FMD

2

Who is refractory to FMD?

Horses

3

What is the morbidity/mortality for FMD?

High morbidity

Low mortatlity

4

Is FMD zoonotic?

Not recognized as zoonotic but can infect humans

5

What is the important to remember about FMD economically?

NOTIFIABLE
Trade barrier, and heavy monetary losses.

6

FMD also stands for what?

Fast moving disease

7

What is the virus name for FMD?

Aphtovirus
Picoviridae

8

How does FMD replicate?

cytoplasm, exits by lysis

9

Who does FMD effect?

Ruminants and swine

10

This disease has 7 serotypes

FMD

11

Are there Vacc for FMD?

Yes-BUT not always efficient bc of the antigenic drift and the amount of serotypes

12

What would happen if you introduced FMD into a niave population?

Shedding starts BEFORE c/s so you wouldn't know.

Stable in the environment-naked

Highly infectious

13

What are your CS for FMD

Fever-can cause abortion from fever

Drop in milk production

Drooling

**Vesicles in tongue, gums, interdigital space, coronary bands, teats

After vescle rupture, ulcerative lesions--secondary infections

14

You have a pig that is lame, what dz can you suspect?

FMD-painful for them to stand

15

What is the main route of infect for FMD?

what are the other ways?

Inhalation of droplets

but also infection from food, contaminated vacc/semen and fomites

16

What is important to remember about the pathogenesis of FMD

Replicates in the pharynx
Followed by viremia which at this point EXCRETION OF VIRUS 24 BEFORE ONSET OF C/S

17

In what animals is FMD persistant in, and how long?

Cattle-2yrs
Sheep 6 mo

NOT in pigs

18

What are you DDx for FMD?

Vesicular stomatitis
Swine vesicular dz
Vesicular exanthema of swine

19

How do you diagnose FMD?

Ag enzyme immunoassay

20

Control for FMD

Vacc in endemic areas
Cull positive or if not culling, the animals has a long recovery

21

What parts of the world do you have FMD?

WW except US and Europe

22

What dz is pestivirus from Flaviviridae

BVD

23

Where do you find BVD?

WW
very important in dairy and beef cattle

24

Whats the morb/mort in BVD?

High morb and mort

25

What disease? Younger animals after maternal ab decline. pankleukopenia.

Other animals diarrhea, nasal and ocular discharge
some erosive stomatitis

drop in milk yield in dairy cows

can cause secondary infections

BVD

postnatal infection of non pregnant cattle

26

What dz?
Transplacental spread.

The outcome depends on the virus stain and the age of the fetus (the immunologic maturity)

BVD of pregnant cows

27

When will calves get the PI and MD of BVD?

Superinfection with a homologous BVDV

Mutation of the ncp to cytopathic cp variant

Vacc with MLV BVD strain homologous to the ncp PI virus they can develop MD

28

At what age do cattle get the MD of PI in BVD?

6-18 mo old

29

What dz?
Biphasic fever, anorexia, tachycardia, polypnea, decreased milk production, watery diarrhea

Feces may have blood and foul odor

Erosions and ulcers on tongue, palate, gingival. Or interdigital regions, coronary bands, teats, vulva and prepuce.

Other signs might be: nasal-ocular discharge, corneal opacity, hypersalivation, decreased rumination and blat

Acute mucosal dz of BVD

30

What dz?
cattle may have intermittent diarrhea, chronic bloat, decreased appetite and weight loss

Nasal-ocular discharge

Chronic mucosal dz of BVD

31

Can cattle survive the MD of BVD?

Rarely

32

What are the 2 biotypes of BVD

cytopathic, and noncytopathogenic

33

Where does BVD primarily replicate?

Tonsils, nasal mucosa.
then to LN, spleen, thymus.

With the high virulence it can go to the T cell dependent areas and BM

34

Which form of BVD is there a persistant viremia?
Why is it persistant?
How does it spread?

noncytopathogenic

It can inhibit interferon 1

Transplacental and intrauterine

35

What kind of samples can you take to diagnose BVD?

feces
nasal discharge
blood
tissue collected from necropsy or aborted fetuses

36

How do you diagnose BVD?

You can have a presumptive dx based on clincal history, reproduction records, c/s, gross and microscopic lesions

Viral Ag detection
RT-PCR

37

What do you need to consider when diagnosing BVD with immunotolerant state of some animals?

The interpretation of seronegative results

38

Control of BVDV?

detect PI animals and cull

39

Do we have vacc for BVDV?

Yes. Attenuated is used mostly.
These can cause PI to develop the MD

40

Deltaretrovirus from Retroviridae is what?

Bovine Infectious Leukosis

41

Who does Bovine Infectious Leukosis infect?

Cows, sheep and goats.

Causes lymphosarcoma in sheep

42

Asymptomatic

30% will develop persistent lymphocytosis with no c/s

__-__ yr of age will develop lymphoid tumors

Lymphosarcomas present on LN, abomasum, heart, spleen, kidneys, uterus, spinal meninges, and brain but where will you not find malignant cells?

Bovine Infectious Leukosis

4-8

wont find malignant cells in the BLOOD

43

What lymphocyte is mostly affected in Bovine Leukosis

B cells

44

Dx of Bovine Infectious Leukosis?

Ab ELISA

45

How is Bovine infectious leukosis spread?

Horizontal transmission requires close prolonged contact.

Iatrogenic

Transplacental?

46

Control of Bovine Infectious leukosis

Test and removal programs in US and Canada

47

Herpesviridae, acelaphine herpesvirus __??

Malignant catarrhal fever

herpesvirus 1

48

What is the genus and family for Malignant catarrhal fever

herpesviridae, acelaphine herpesvirus 1

49

What dz do you see infection in Africa and in zoos from subclinical wildebeest? esp during calving times

Malignant Catarrhal fever

50

What dz can you see outside Africa, in close contact with sheep at lambing?

Malignant catarrhal fever

51

What dz can you see in feedlot cattle in US with no conatct with sheep with minor epidemics

Malignant like catarrhal fever

52

Bilateral ophtalmia
Generalized lymphadenopathy
Extensive mucosal erosions
Diarrhea and CNS signs

Malignant Catarrhal fever

53

Dx of Malignant catarrhal fever?

History and C/S

54

Dx of Malignant catarrhal fever?

History and C/S

Confirmed by virus isolation in calf thryoid cells

55

How can you control Malignant catarrhal fever?

Cattle are dead end with transmission being ineffective

56

What is the family genus name for BVD

Pestivirus

Flaviviridae

57

What is the family genus name for FMD?

Picornaviridae

Apthovirus