Quiz #3 SCI / parkinsons/MS Flashcards
(43 cards)
MS with ataxia- focus on
Stability
PD with rigidity- focus on
Mobility
Where is the substantia nigra located?
: Basal Ganglia
What are the primary responsibilities of the basal ganglia?
Regulation of posture and movement
What causes the primary symptoms in parkinsons disease?
A decrease in dopamine stored in the substantia nigra
Lesions in the basal ganglia cause
change in the character of movement, rather than produce weakness or paralysis.
Secondary Parkinsonism occurs as a result
other conditions (encephalitis, alcoholism, exposure to toxins etc)
inability to initiate movement
Akinesia
”: constant resistance to passive limb movement in any direction regardless of speed
Lead-pipe rigidity
causes a catch & release; result of combining lead-pipe rigidity and tremor
Cogwheel”:
often the first sign of PD
Tremor
Gait of a person with PD
shuffling, punctuated by short steps and progressive increase in speed. FESTINATING GAIT
Fatigue contributes to…in PD
postural instability b/c of the difficulty the person with PD experiences while trying to sustain an activity.
Hoehn & Yahr Classification
Stage 0
No signs of disease
Hoehn & Yahr Classification
Stage 1
Unilateral disease
Hoehn & Yahr Classification
Stage 1.5
Unilateral plus axial involvement
Hoehn & Yahr Classification
Stage 2
Bilateral disease w/o impairments of balance
Hoehn & Yahr Classification
Stage 2.5
Mild bilateral disease w recovery on pull test
Hoehn & Yahr Classification
Stage 3
Mild to moderate bilateral disease with recovery on pull test
Hoehn & Yahr Classification
Stage 4
severe disability; still able to walk or stand unassisted
Hoehn & Yahr Classification
Stage 5
w/c bound or bedridden unless aided
is the major mainstay in the Rx of PD.
Levodopa (L-dopa)
Works best to decrease rigidity and make movement easier
Works for only 5-7 years before effectiveness decreases
often used as the first medications after DX of PD to slow the progression
Selegiline or rasagiline (Azilect)
Primary PT goal of PD
to maximize function in the face of progressing pathology