Quiz 4

Question 1

MC cause of viral enteritis? in children?

Answer 1

Norwalk virus

Rotavirus in infants and young children

Question 2

Staph aureus - what kind of poisoning?

Answer 2

picnic food poisoning

Question 3

Bacillus cereus - what kind of poisoning?

Answer 3

contaminated rice or meat

Question 4

Vibro (cholera and non-cholera) - what kind of poisoning?

Answer 4

saltwater crabs and shrimp

Question 5

Clostridium botulinum - what kind of poisoning?

Answer 5

homecanned fruits and vegetables

Question 6

MC cause of foodbourne illness in US

Answer 6

Norovirus

Question 7

2nd MC cause of foodbourne illness in US

Answer 7

Salmonella

Question 8

multiple polyps in GI, majority non-neoplastic, harmartomatous, self-limiting, and benign, increased risk of developing adenocarcinoma

Answer 8

juvenile polyposis syndrome

Question 9

Inherited condition with hundreds to thousands of polyps form mainly in epithelium of large intestine

Answer 9

familial adenomatous polyposis

Question 10

nests of elongated spindle cells

Answer 10

leiomylomas

Question 11

frond-like appearance with stromal/smooth muscle core that is covered by acinar glands and normal mucosa

Answer 11

Peutz-Jeghers syndrome

Question 12

glands irregular and very crowded. crowded nuclei w hyperchromatism and pleomorphism. lumens contain bluish mucin. loss of goblet cells

Answer 12

Adenocarcinoma

Question 13

Familial adenomatous polyposis is part of ___ syndrome

Answer 13

Gardener’s

Question 14

Gross appearance of carcinoid tumors

Answer 14

Smooth and well-circumscribed

Question 15

Carcinoid tumors secrete ____

Answer 15

serotonin

Question 16

cauliflower like appearance

Answer 16

villous adenoma

Question 17

step of liver disease that involves swollen hepatocytes with wispy cleared cytoplasm, irregularly clumped organelles, and large clear spaces

Answer 17

ballooning degeneration

Question 18

Councilman bodies are associated with

Answer 18

apoptotic cell death

Question 19

In fibrosis, deposition of ____ affects blood flow

Answer 19

collagen

Question 20

Isolated hepatocyts that coalesce to form shrunken, intensely eosinophilic staining cells containing fragmented nuclei

Answer 20

councilman bodies

Question 21

hepatocytes that accumulate keratin and other proteins, which become visible as eosinophilic cytoplasmic inclusions

Answer 21

Mallory bodies

Question 22

hazy staining appearance with diffuse granular cytoplasm

Answer 22

ground glass hepatocyte

Question 23

Ground glass hepatocytes commonly seen with

Answer 23

chronic Hep B

Question 24

Councilman bodies are associated with these diseases

Answer 24

yellow fever and other viral infections

Question 25

Mallory bodies may be seen in

Answer 25

NASH, primary biliary stenosis, Wilson's, and hepatocellular tumors

Question 26

Associated with episodic elevations in aminotransferases

Answer 26

Hep C

Question 27

Type of hepatitis associated with hepatocellular carcinoma

Answer 27

Hep B

Question 28

MC chronic blood bourne infection in US

Answer 28

Hep C

Question 29

Causes of chronic hepatitis

Answer 29

``` A = AI hepatitis and alpha 1-antitrypsin deficiency B = Hep B and Biliary cirrhosis C = Hep C and Copper overload (Wilson’s disease) D = Drugs E = ETOH F = Fe overload (Hemochromatosis) ```

Question 30

caused by HAV infx or non-hepatotropic virus (such as HSV) reactivating latent HBV infx

Answer 30

fulminant hepatitis

Question 31

fulminant hepatitis can also be caused by _____, principally ______

Answer 31

drugs, acetomenaphen

Question 32

IN NAFLD, the AST to ALT ratio is usually

Answer 32

<1

Question 33

inhibits proteases (particularly lung elastase) and other proteases which are normally released from neutrophils at sites of inflammation

Answer 33

alpha 1-antitrypsin

Question 34

AI dz with T cell mediated destruction of bile ducts and liver

Answer 34

primary biliary cirrhosis

Question 35

necrotic areas have mushy red appearance with blotchy bile staining

Answer 35

fulminant hepatitis

Question 36

Bronze diabetes

Answer 36

hemochromatosis

Question 37

segmental stricture and dilation of bile ducts - beaded appearance w barium

Answer 37

primary sclerosing cholangitis

Question 38

Important identifying lab for PBC

Answer 38

anti-mitochondrial antibody test

Question 39

Hyperplastic polyps are frequently observed in these 2 parts of GI tract

Answer 39

duodenum and proximal ileum

Question 40

Inflammation of the liver (hepatitis) is characterized by ____ migrating into specific areas of the peripheral parenchyma

Answer 40

lymphocytes

Question 41

In fulminant hepatitis, hepatic insufficiency progresses from onset of symptoms to hepatic encephalopathy within ____ weeks

Answer 41

2-3

Question 42

metabolite of acetomeniphen? | conversion increased by what?

Answer 42

N-acetyl-p-bezoquinone-imine (NAPQI) | alcohol

Question 43

NAFLD contributes to the progression of Hep ___

Answer 43

hep C

Question 44

____ is a complication in NASH

Answer 44

cirrhosis

Question 45

Kayser-Fleischer's rings are pathognomic

Answer 45

Wilson's

Question 46

round or oval cytoplasmic globular inclusions in hepatocytes. periportal red hyaline globules.

Answer 46

alpha 1-antitrypsin deficiency

Question 47

Granulomatous destruction of medium sized intrahepatic bile ducts; sheets of inflammatory cells have obliterated the portal tracts

Answer 47

PBC

Question 48

Classic onion skin fibrosis causes obliteration of the bile ducts

Answer 48

PSC

Question 49

Associated with hepatomegaly, xanthomas, and xanthelasmas

Answer 49

PBC

Question 50

Associated with ulcerative colitis and increased risk of cholangiocarcinoma

Answer 50

PSC (70%)

Question 51

Associated with rheumatoid arthritis and Sjogren's

Answer 51

PBC

Question 52

Peutz-Jeghers syndrome associated with mutation of ___ gene

Answer 52

LKB1

Question 53

MC small bowel tumor in US

Answer 53

adenocarcinoma (large bowel is most common site for tumors though)