QUIZ 5 Part 1 Flashcards
(24 cards)
responsible for the removal of metabolic
waste and the maintenance of water and
electrolyte balance. Functional unit of the kidney
Nephrons / malphigian bodies
tells how healthy the kidney is
Glomerular filtration rate
Normal Filtration rate of the body
GFR:125mL/min (180 L/day)
Fullfills most of the criteria needed. It is the standard reference in GFR measurement
Inulin
Negative about insulin
Time consuming
Its clearance is used most extensively. it is the by product of muscle metabolism
Creatinine
Reabsorption of water and active secretion of some weak electrolyte ( weak acids)
Active renal secretion
Where ACTIVE RENAL SECRETION occurs
proximal Convoluted tubule
ACTIVE RENAL SECRETION requires energy and a carrier T/F
True
Drugs used to measure active tubular secretion
P-amino hippuric acid (PAH) and iodopyracet (Diodrast)
P-amino hippuric acid (PAH) and iodopyracet (Diodrast) are filtered by the glomeruli and secreted by tubular cells T/F
True
Where TUBULAR REABSORPTION occurs
Distal convoluted Tubule
The reabsorption of drugs that are acids or weak bases is influenced
by?
pH of fluid (urine pH)
pKa of the drug
WA + acidic urine=
non-Ionized (reabsorbed)
WB + alkaline urine=
non-ionized (reabsorbed)
WA + alkaline urine (vice versa)=
ionized (excreted)
Measurement of change in concentration of solutes in perfusion
fluid
A. In- vitro Method
Isolated tubule preparation
Measurement of urine volume and sodium excretion
In-vivo Method
Lipschitz test
Measurement of electrolytes excretion
Saluretic activity
Allows localization of tubular site of
action
Micropuncture techniques
Amount of filtrate going through the glomerular membrane in one minute
GFR
Also known as anti-diuretic hormone
Vasopressin
Hormone responsible for RAAS
Renin
