QUIZ TOM

Question 1

TSH is synthesized in

Answer 1

Thyrotrophs

Question 2

A-unit

Answer 2

FSH, LH, HCG

Question 3

B-unit attaches to thyroid receptors & stimulate:

Answer 3

Growth and vasculature of the thyroid gland
Promotes release of stored thyroid hormones
Uptake and organification of iodine

Question 4

Best thyroid function test

Answer 4

IRMA

Question 5

TSH is detectable in

Answer 5

Serum of thyrotoxic px

Question 6

LH & FSH in secreted by

Answer 6

Gonadotropic cells

Question 7

Funtion of FSH in F

Answer 7

Stimulates growth & maturation of ovarian follicle
Promotes secretion of estrogen
Promotes endometrial changes characteristic of the 1st portion of mens cycle

Question 8

Function of LH in F

Answer 8

Promotes maintenance of 2nd portion
Release of ova
Transformation of follocle into the corpus luteum after ovulation

Question 9

3 cycle of mens

Answer 9

Follicular
Ovulatory
Luteal

Question 10

function or FSH in M

Answer 10

Stimulates spermatogenesis
Stimulates testicular growth
Production of ABP by the sertoli cells

Question 11

Funtion LH in M

Answer 11

Production of testosterone by the leydig cells

Question 12

Methods for determining LH & FSH

Answer 12

RIA kits (serum, plasma, urine sample)
• pooled blood sample
•multiple serial blood sample
•timed sample of urine

Question 13

Prolactin is secreted by

Answer 13

Luteotropin
Milk letdown reflex
•lactation
•pregnancy
•post pubertal women

Question 14

Prolactin function

Answer 14

Promites milk production

Question 15

Circadian fashion

Answer 15

Increased in sleep
Decrease in 10am-12noon

Question 16

Pulsatile fashion

Answer 16

3 specimens with 20-30 mins interval

Question 17

Measurement of prolactin

Answer 17

Major circulating form: non-glycosylated monomer
•big prolactin
•macroprolactin with immunoglobulin

Question 18

Method for prolactin

Answer 18

Immunoassay following PEG extraction and centrifugal ultrafiltration

Question 19

Weak lipolytic effect

Answer 19

Lipotropin

Question 20

Opioid peptides with pain-alleviation

Answer 20

Beta-endorphin & metenkephalin

Question 21

Control melanin

Answer 21

Melanocyte-stimulating hormone

Question 22

Controls the secretion or hormones from the adrenal cortex

Answer 22

Adrenocorticotropic hormone

Question 23

ACTH is regulated by

Answer 23

Corticotropin-releasing hormone

Question 24

Posterior pituitary AKA

Answer 24

Neurohypophysis

Question 25

Pos. Pituitary secretes

Answer 25

AVP & oxytocin

Question 26

AVP & oxytocin synthesized in

Answer 26

Hypothalamus (paraventricular & supraoptic nuclei)

Question 27

Hypothalamic diabetes insipidus AKA

Answer 27

Neurogenic, cranial/central diabetes insipidus

Question 28

Caused by failure of the pituitary gland to secrete normal amount of AVP

Answer 28

Hypothalamic diabetes insipidus

Question 29

Failure of the kidney to respond to normal or increased conc. of AVP

Answer 29

Nephrogenic diabetes insipidus

Question 30

Chronic and excessive intake of water Hypothalamic disease affecting the thirst center of the brain

Answer 30

Psychogenic or primary polydipsia

Question 31

Psychogenic or primimary polydipsia can cause

Answer 31

Hypotonic polyuria

Question 32

Meaning of SIADH

Answer 32

Syndrome of inappropriate antidiuretic hormone

Question 33

plasma conc. is increased without stimuli

Answer 33

SIADH

Question 34

SIADH will result to

Answer 34

Malignancy Acute and chronic dse. of the CNS Side effects of drugs

Question 35

Nephrogenic diabetes insipidus acquired forms

Answer 35

Metabolic disorders Drugs & renal dse.

Question 36

Hypothalamic diabetes insipidus is associated with

Answer 36

Neoplastic dse. Surgery Head trauma Hypoxia Granulomatous dse. Infections & autoimmune dse.