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Undeleted > Racemic Epinephrine (Vaponephrine) > Flashcards

Racemic Epinephrine (Vaponephrine) Flashcards

1
Q

Drug Classification

A

Sympathomimetic

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2
Q

Mechanism of Action

A

Alpha and Beta agonist, (slightly beta2 selective) ->bronchodilation, decreased mucous membrane secretions, relieves subglottic edema

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3
Q

Pharmacokinetics

A
  • Onset of Action- <5 minutes inhaled
  • Peak Effects- 5-15 minutes
  • Duration of Effects- 1-3 hours
  • Half-Life- N/A
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4
Q

Indications/Field Use

A

-Croup (Laryngotracheobronchitis)

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5
Q

Contraindications

A

Epiglottitis

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6
Q

Side Effects/Adverse Reactions

A

Restlessness/anxiety
Dizziness/headache
HTN/Tachycardia
N&V

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7
Q

Dose

A

PEDI:
5mg Epi 1:1000 in 2.5-3.0mL NS, nebulized with oxygen
-or-
0.25-0.75mL of 2.25% solution in 2mL NS nebulized with oxygen

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8
Q

Precautions

A

Rebound effects following clearance of medications

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9
Q

Drug-Drug Interactions

A

Additive effects with other sympathomimetics

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