Radiographic Signs:Patterns Of Bone Destuction Flashcards

1
Q

What are the various features of geographic lesions?

A
Centric or Eccentric
Expansile or Non expansile
Compartment or non-compartment 
Speckled or radiolucent or 
Isodense
well or ill-defined
Thin or thick sclerotic margin
Benign or malignant
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2
Q

Category of geographic lesion:

Well defined margin w/ sclerotic rim

Short zone of transition

Benign

A

1A

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3
Q

Bone lesion:

Slow growing and benign (can spread)

Larger > 1cm in size

Zone of transition is an indicator of its aggressiveness

Base lesion is radiolucent area lesion

A

Geographic

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4
Q

Category of Geographic lesion:

Well defined margin w/o sclerotic rim

More aggressive lesions > 1A

Wider transitional zone at the margin >1A

Benign

A

1B

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5
Q

Prime example cause of 1B geographic lesion

A

Osteomyelitis

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6
Q

Category of geographic lesion:

Ill-defined margin

Wide zone of transition

Aggressive, often malignant`

A

1C

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7
Q

When examining the x-ray above, need to know ALAS “a foxism”

A

Age

Location
Appearance

Symptom

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8
Q

When internal matrix has the same density as the medullary cavity

A

Isodense

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9
Q

Causes of Lesions:

Benign or malignant, are common causes of Geographic Lesion

Can destroy right up to the articular margin, but will not touch the joint
- subarticular

A

Tumors

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10
Q

Causes of Lesions:

(can be very dangerous)- full of plasma fluid (as opposed to cells)

Can destroy right up to the articular margin, but will not touch the joint
- subarticular

A

Tumor-like lesions

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11
Q

Causes of Lesions:

No respect for anything (ie. Joints) unlike tumors

Does not stop at subchondral bone, would continue into joints

A

Osteomyelitis-Bone infection

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12
Q

What are the main destroyers of bone?

A

Infection and tumor

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13
Q

What ways do destructive bone lesions occur?

A

Replacement of bone with tissue or fluid

Removed by lytic enzymes

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14
Q

T/F: Infections can replace bone with tissue or fluid and remove bone by lytic enzyme activity.

A

True

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15
Q

What is the minimum loss of bone required to see on plain film?

A

30%

50% in the spine

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16
Q

What is the minimum loss required to see on MRI?

17
Q

Bone lesion:

Individual lesions <1cm

Well defined with NO sclerotic margin (usually considered 1B)

Usually in flat bones, especially in cranial fault. (can be in spine)

A

Punched-out

18
Q

What is the classic cause of punched out lesion?

A

Multiple Myeloma

19
Q

Appearance of punched-out lesions in the skull?

A

Scattered

usually of uniform size

20
Q

T/F: Punched-out lesions are usually part of myeltomatosis, which is wide spread loss of bone density

21
Q

Bone Lesion:

Holes 2-5mm

Malignant-rapid growth

Ragged border/wide zone of transition

May be benign (Osteomyelitis) or malignant (Osteosarcoma)

Freq. coexist w/ permeative

A

Moth eaten

22
Q

Cause of Moth eaten

A
Multiple Myeloma
Metastasis
Lymphoma
Ewing's sarcoma
Osteomyelitis
Osterolytic sarcoma
23
Q

Most common 1* bone malignancy

A

Multiple myeloma

24
Q

Primary lymph malignancy that spreads to bone but rarely starts in
bone.

25
Primary bone malignancy classified as a round cell malignancy 4th most common primary bone malignancy Primarily in children – 1st most common in first decade Usually permeative lesion
Ewing's sarcoma
26
Moth eaten and permeative bone lesion has to affect the cortex to be seen on film. How will the cortex appear?
The cortex will be thinned and radiolucent
27
Bone Lesion: <1mm in size Ill-defined Worm holes small, tiny holes Wide zone of transition with fine margins Localized bone pain Occurs in diaphysis
Permeative Osteolysis
28
In which category of bone lesion will the pt have bone pain?
Moth eaten Permeative
29
Causes of permeative lesions
Lymphoma Ewing's** Multiple Myeloma Osteomyelitis Neuroblastoma(Metastatic Osteolytic sarcoma
30
This cause of moth eaten and permeative lesions, comes from the adrenal glands, occurs 80% in children under 5 with a strong tendency to metastasize to bone
Neuroblastoma (METs)
31
What disease does neuroblastoma come second to in children under 5?
Wilm's tumor