RADIOPHARMACEUTICALS (Updated) Flashcards

(41 cards)

1
Q

Most commonly used radionuclide generator in nuclear medicine practice worldwide since its first commercial introduction in 1965

A

99 Mo - 99m TC Generator

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2
Q

It is mainly used for lung ventilation scans and for the assessment of cerebral blood flow

A

Xenon-133

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2
Q

The most common applications of Indium-111 are in __________

A

Labelling Blood Cells for Imaging Inflammatory Processes, Thrombi, and Proteins

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2
Q

It was approved for the treatment of patients with relapsed or refractory, low-grade or follicular B-cell NHL

A

Indium-111 and Yttrium-90 Ibritumomab Tiuxetan (Zevalin)

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2
Q

This is used for liver imaging

A

Yttrium-90 Labeled Microspheres

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3
Q

It is eluted from the the Technetium 99m - Molybdenum 99 Generator with sterile isotonic saline

A

Technetium 99m-Sodium Pertechnetate

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4
Q

Technetium 99m-Sodium Pertechnetate is used for:

A
  1. Meckels Diverticulum Scintigraphy
  2. Gastric Emptying Study
  3. Salivary Gland Scintigraphy
  4. Lachrymal Duct Scintigraphy
  5. Thyroid Scintigraphy
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5
Q

The two (2) commonly used diphosphonate compounds are:

A
  1. Methylene Diphosphonate (MDP)
  2. Hydroxymethylene Diphosphonate (HDP)
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6
Q

What radiopharmaceutical is used for renal studies and glomerular filtration rate (GFR) determination ?

A

Technetium-99m Diethylenetriaminepentaacetic Acid (DTPA)

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7
Q

It used to diagnose renal infection in children and in morphological studies of the renal cortex

A

Technetium-99m Dimercaptosuccinic Acid (DMSA)

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8
Q

It was introduced initially under the brand name Cardiolite as a technetium-based radiopharmaceutical to replace Tl-201 in myocardial perfusion imaging.

A

Technetium-99m Methoxyisobutyl Isonitrile (SESTAMIBI)

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9
Q

Used in the diagnosis of myocardial perfusion
abnormalities in patients with coronary artery
disease.

A

Techenetium-99m Tetrofosmin

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10
Q

Primarily used in brain perfusion imaging, although it is used for leukocyte labeling
substituting 111 In-oxine.

A

Technetium-99m Hexamethylpropylene Amine Oxime (HMPAO)

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11
Q

What radiopharmaceutical is used to evaluate hepatocyte function, rule out or prove acute cholecystitis, demonstrate commo bile duct partial or complete obstruction, and verify hepatic bile duct atresia in infants ?

A

Technetium-99m Iminodiacetic Acid (IDA)

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11
Q

The radiopharmaceutical of choice for lung perfusion scan with ventilation scan to
EXCLUDE pulmonary embolism

A

Technetium-99 m Macroaggregated Albumin (MAA)

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12
Q

99m TC HSAM is used for (2):

A
  1. Pulmonary Perfusion Scintigraphy
  2. Determination of Right-to-left Shunts
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13
Q

HSAM stands for

A

Human Serum Albumin Microspheres

13
Q

It is used for pulmonary perfusion scintigraphy and determination of right-to-left shunts

A

Technetium-99m Human Serum Albumin Microspheres (HSAM)

13
Q

99m TC Sulfur Colloid is used for (4):

A
  1. Bone Marrow
  2. Spleen Scintigraphy
  3. Liver Scintigraphy
  4. Lymphoscintigraphy
14
Q

This RPM is commonly used for: Bone Marrow Spleen Scintigraphy, Liver Scintigraphy, Lymphoscintigraphy

A

Tc-99m Sulfur Colloid

14
Q

Which RPM is used for Lung Perfusion Scan ?

BONUS Q: MAA stands for ?

A

Tc-99m MAA

BONUS Ans: Macroaggregated Albumin

14
Q

This comprises indications such as GI BLEEDING, Radionuclide Ventriculography, and Hepatic HEMAngioma

A

Tc-99m RBC

(Once you see the words bleeding and the prefix hema, deretso kana sa red BLOOD cells na concept para RBC)

14
Q

Which RPM is used for Skeletal Imaging ?

A

Tc-99m MDP/HDP

15
Q

It covers indications such as Renal Scintigraphy, Lung Ventilation (Aerosol) and GFR scan

15
_______ is used for Renal Dynamic Scintigraphy whereas _____ is used for Renal Cortical Scintigraphy
Renal DYNAMIC Scintigraphy = Tc-99m MAG3 Renal CORTICAL Scintigraphy = Tc-99m DMSA
16
It is mainly used for Hepatobiliary Scintigraphy
Tc-99m HIDA
17
Which RPMs cover Myocardial Perfusion Scintigraphy and Parathyroid Scintigraphy (3) ?
1. Tc-99m SESTAMIBI 2. Tc-99m TETROFOSMIN 3. TI 201
18
This is used for WBC Labelling and Cerebral Perfusion Scintigraphy
Tc-99M HMPAO
19
This is used for Cerebral Perfusion Scintigraphy only
Tc-99m ECD
20
What are the two RPMs for Lung Ventilation (Aerosol) only ?
1. Xe-127 2. Xe-133
21
This is mainly used for Lung Ventilation Scan ?
Kr-81m
22
Which RPM is used for: Thyroid Imaging, Whole Body Scan, and Thyroid Uptake Studies ?
I-131 Sodium Iodide
23
Which RPM is used for Diagnosis of Thyroid CA (Cancer), and Parathyroid Scintigraphy ?
I-123 Sodium Iodide
24
This RPM is used for Inflammation Disease and Infection Detection ?
In-111 Oxine Leukocytes (RATIONALE: Inflammation is dealt with Leukocytes / White Blood Cells. Pag nakita mo na ang inflammation, Leukocyte agad isipin mo.)
25
B-cell Lymphoma Imaging is used with what RPM ?
I-131 Tositumomab (Bexxar)
26
Which is used for Adrenal Medullary Tumor Imaging ? A. MIBG B. NP-59 C. Pentetreotide D. DaTscan
A. MIBG
27
Adrenal Imaging is used with what RPM ? A. MIBG B. NP-59 C. Pentetreotide D. DaTscan
B. NP-59
28
This is used for Somotostatin Receptor Tumor Imaging A. MIBG B. NP-59 C. Pentetreotide D. DaTscan
C. Pentetreotide
29
This is used as a Dopamine Transporter, for Parkinson's Disease Imaging, and Parkinsonia Syndrome Imaging A. MIBG B. NP-59 C. Pentetreotide D. Ioflupane (DaTscan)
D. Ioflupane (DaTscan)
30
Which RPM can be used for the treatment of: Grave's Disease, Toxic Nodule, and Thyroid CA ?
I-131 Sodium Iodide
31
What are the two RPMs intended for B-cell Lymphoma Treatment ?
1. I-131 Tositumomab (Bexxar) 2. I-111 Ibritumomab (Zevalin)