Random Flashcards

(27 cards)

1
Q

what conditions is growth hormone given for

A

Turners syndrome
Prader-Willi
Proven growth hormone deficiency

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2
Q

what can decrease the absorption of levothyroxine

A

Iron supplements

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3
Q

what cardiac problems can hyperthyroidism cause

A

high output cardiac failure

AF

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4
Q

genetic profile Kleinfelters

A

47 XXY

- High LH, low testosterone

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5
Q

symptoms of Kleinfelters

A
tall
lack of secondary sexual characterises
small, firm testis 
infertile
gynaecomastia
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6
Q

drug given in cerebral metastasis

A

dexamethasone to decrease cerebral oedema

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7
Q

what causes impaired hypoglycaemic awareness in patients with diabetes

A

neuropathy of autonomic nervous system

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8
Q

blood glucose targets T1DM

  • on waking
  • before meals
A

5-7 mmol on waking

4-7 mmol before meals

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9
Q

what is Nelsons syndrome

A

a pituitary adenoma releasing ACTH after bilateral adrenalectomy

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10
Q

HbA1c range for pre-diabetes

A

42-47 mmol

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11
Q

what is secondary hypothyroidism due to? what do thyroid function tests show?

A

pituitary insufficiency

low TSH low T4

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12
Q

What drugs can cause galactorrhea

A

metoclopramide
domperidone
chlorpromazine

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13
Q

what is a neuroblastoma

A

tumour of neural crest of adrenal medulla

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14
Q

when does a neuroblastoma present?

how does it present?

A

median age 20 months old

  • abdo mass
  • weight loss
  • pallor
  • bone pain
  • hepatomegaly
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15
Q

what is raised in a neuroblastoma

A

VMA + HVA levels

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16
Q

1st line treatment of a prolactinoma

A

bromocriptine

17
Q

what diabetic drug increases risk of fractures

18
Q

mechanism of action orlistat

A

inhibits gastric + pancreatic lipase

- aids weight loss

19
Q

features of MEN 1

A

parathyroid adenoma
pituitary adenoma
pancreatic tumour

20
Q

features of MEN 2

A

phaeochromocytoma
medullary thyroid cancer
parathyroid adenoma

21
Q

what happens to dose of hydrocortisone + fludrocortisone if patient with Addisons becomes unwell

A

double hydrocortisone dose

fludrocortisone dose remains the same

22
Q

pepper pot skull indicates what pathology?

A

primary hyperparathyroidism

23
Q

tender goitre indicates what?

A

subacute thyroiditis

24
Q

what is Waterhouse friderichsen syndrome

A

adrenal gland failure due to bleeding into the adrenal gland

- typically caused by meningitis

25
treatment of toxic multi nodular goitre
radioactive iodine
26
how many units of insulin are in 1ml
100
27
what is Kallmans syndrome
genetic GnRH deficiency | - associated with anosmia