Random Drug Knowledge

Question 1

Drugs that cause Agrnulocytosis

Answer 1

Atypical - Clozapine 
AED - carbamazepine 
Cytotoxic - methotrexate 
Ax - penicillin / co-trimoxazole / chloramphenicol
Anti-depressant - Mirtazapine
Anti-Thyroid - Carbimazole

Question 2

Monitoring on statin

Answer 2

LFT baseline, 3 months, 12 months

Question 3

Monitoring ACEI

Answer 3

U+E baseline
Change in dose
Annual

Question 4

Monitoring amiadarone

Answer 4

TFT, U+E, LFT, CXR baseline

TFT + LFT every 6 months

Question 5

Monitoring methotrexate

Answer 5

FBC, U+E, LFT prior to starting and weekly till stable

Then 2-3 months

Question 6

Monitoring azathioprine

Answer 6

FBC + LFT prior

Then every 3 months

Question 7

Monitoring lithium

Answer 7

TFT + U+E prior and every 6 months

Lithium level until stable then 3 monthly

Question 8

Monitoring Sodium valrpoate

Answer 8

LFT anf FBC prior

LFT every 6 months

Question 9

Monitoring Glitazone

Answer 9

LFT prior and regular

Question 10

What drugs cause impaired glucose tolerance

Answer 10

BB 
Thiazide
Steroid
Tacrolimus
Interferon Alpha
Anti-psychotics

Question 11

What drugs cause drug induced thrombocytopenia

Answer 11

Heparin
Abiximab 
NSAID
Diuretic - furosemide 
Ax - rifampicin, sulphonamide, penicillin
AED - carbamazepine / valproate

Question 12

What drugs can cause urinary retention

Answer 12

Anti-cholinergic 
TCA
Opiods
NSAID
Alcohol 
Benzo 
Spinal
Epidural

Question 13

What drugs cause lung fibrosis

Answer 13

Amiadarone
Nitranfurantoin
Dopamine agonist 
Methotrexate
Sulfasalsine

Question 14

What drugs cause photosensitivity

Answer 14

Thiazide
Amiadarone
Ax - tetracycline, cipro, sulphonamide
Sulphonurea

Question 15

What drug cause cataract

Answer 15

Steroid

Question 16

What drug cause optic neuritis

Answer 16

Ethambutol
Amiadarone
Metronidazole

Question 17

What drug cause retinopathy

Answer 17

Hydroxychloroquine

Quinine

Question 18

p450 inhibitors (increase warfarin)

the A’s

Answer 18

Acute alcohol
Amiadarone 
Allopurinol 
Anti-depressant - SSRI 
Ax - cipro / erythromycin / co-trimox / metronidazole 
Anti-fungal - azole

Other 
Cranberry 
NSAID 
Isonazid
Omeprazole
Sodium valproate

Question 19

p450 inducers (decrease warfarin and OCP)

Answer 19

Vit K
AED - carbamazepine / phenytoin
Barbiturates
Rifampicin 
St Johns wort
Smoking
Chronic alcohol

Question 20

White and black square BNF

Answer 20

Less suitable to prescribe

Question 21

Black triangle down BNF

Answer 21

Newly licensed

Question 22

NHS with line through

Answer 22

Not prescirbale on NHS

Question 23

Square with PoM

Answer 23

Prescription only

Question 24

Square with CD

Answer 24

Controlled drug

Question 25

When do you get digoxin level

Answer 25

6 hours post dose

Question 26

When would you get trough level of phenytoin

Answer 26

Adjusting dose Toxicity Detecting non-adherance Regular monitoring not require

Question 27

When do you get lithium

Answer 27

12 hours post dose

Question 28

When do you get ciclosporin

Answer 28

Immediately before dose