Random Qs Flashcards
(21 cards)
Neuroleptic Malignant Syndrome Symptoms
1) delirium & mental status change (early)
2) autonomic instability (tachydcardia) 3) m. rigidity
4) myoglobinuria 5) hyperpyrexia
Serotonin Syndrome
1) muscle rigidity 2) hyperthermia 3) CV collapse
AA Metabolism Rxns needing B6
1) DOPA-> Dopamine (DOPA decarboxylase) 2) tryptophan-> niacin 3) histidine -> histamine 4) glycine-> porphyrin 5)Glutamate-> GABA
6) homocysteine -> cystathioneine
histamine AA precursor
histidine
porphyrin, heme AA precursor
glycine
NO AA precursor
arginine
GABA AA precursor
Glutamate
SAM AA precursor
methionine
creatine AA precursor
arginine
arginine precursor of…
NO, urea, & Cr
urea AA precursor
arginine
glutathione AA precursor
glutamate
niacin AA precursor (NAD+/NADP+)
tryptophan *need B6
serotonin/melatonin AA precursor
tryptophan
Symptoms of Hyperammonia (due to OTC def/ liver disease)
slurred speech, somnolence, vomiting, cerebral edema, blurring of vision
tx of OTC def
low protein diet, biotin, benzoate, phenylbutyrate
Dopamine to NE uses what vitamin as a cofactor(dopamine beta-hydroxylase)
Vit C (vs. B6 for dopa-> dopamine (or BH4 in phenl-> tyro-> dopa
what does cortisol activate?
NE-> EPI conversion (use SAM as cofactor)
glutamine is N source for
pyrimidine de novo synthesis in cytosol w/ carbamoyl phosphate synthetase II
Secretory products of: G cell, I cell, S cell, D cell, Parietal cell?
G: gastrin I: CCK S: Secretin D: somatostatin Parietal: Gastric Acid + IF
vit e other name and fn
alpha-tocopherol (antioxidant by preventing nonenzymatic oxidation of cell components by oxygen free radicals) esp rbcs
