Rapid Review Relevant Treatments Flashcards by Diana Mantilla

ethylene glycol/methanol intoxication

fomepizole (alcohol dehydrogenase inhibitor)

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chronic hep B or C

IFNa (HBV & HCV)
ribavirin, simeprevir, sofosbuvir (HCV)

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s bovis

penicillin prophylaxis
eval colon cancer if linked to endocarditis

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C botulism

human botulinim immunoglobulin

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C tentani

antitoxin and wound debridement

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hae infl b

amoxicillin + clavuclanic acid (mucosal infections)
ceftriaxone (meningitis)
rifampin (prophylaxis)

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N gonorrhea

ceftriaxone (+ azithromycin/doxycycline to cover concurrent C trachomatis)

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N meningitis

pencillin/ceftriaxone
rifampin/ciprofloxacin/ceftriaxone (prophylactic)

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legionella

macrolides (azithromycin or fluoroquinolones)

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psedomonas

piperacillin-tazobactam, cephalsporins, monobactams, fluroquinolones, carbapenems

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treponema pallidum

penicillin G

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chylamidia trachomatis

azithromycin/doxycycline (+ ceftriaxone for coinfection w/ gonorrhea)
oral erythromycin to treat chlamydial conjunctivitis in infants

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candida albicans

topical azoles (vaginitis)
nystatin, fluconazole, caspofungin (oral)
fluconazole, caspofungin, amph B (esophageal/systemic)

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cryptococcus neoformans

induction w/ amph B and flucytosine, maintance w/ fluconazole (in AIDS+)

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sporothrix schenckii

itraconazole, oral potassium iodide

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pneumocystis jirovecii

TMP-SMX (prophylasis + treatment in immuno suppressed, CD4<200)

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toxoplasma gondii

sulfadizaine + pyrumethamine

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malaria

chloroquine, mefloqunine, atovaqunone/proguanil (blood schizont)
primiquine (liver hpnozoite)

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trichamonas vaginalis

metronidazole (patient and partners)

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strept pyogenes

penicillin prophylaxis

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strept pneumo

penicillin/cephlosporin (systemic infection, pneumo)
vancomycin (meningitis)

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staph aureus

MSSA: nafillin, oxacillin, dicloxacillin (antistaph penicillins)
MRSA: vancomycin, daptomycin, linezolid, ceftroline

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enterococci

vancomycin, aminopenicillins/cepf
VRE: daptomycin, linezoloid, tigecycline, streptogramins

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rickettsia rickettsii

doxycycline, chloramphenicol

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mycobacterium TB

Rifampin- red/orange body fluids Isoniazid- vit B6 def, hepatotoxic Pyrazinamide- gout Ethambutol- optic neuropathy (red/green color blind) **2nd line streptomycin- tinnitus/vertigo

UTI prophyalaxis

TMP-SMX

influenxa

oseltamivir zanamivir

CMV

ganciclovir, foscarnet, cidofovir

PDA

close> indomethacin open> PGE

stable angina

sublingual nitroglycerin

hypercholesterolemia

stain (1st line)

hypertriglycerides

fibrate

arrhythmia in damaged cardiac tissue

Class 1B anti-arryhtmic (lidocaine, mexiletine)

prolactinoma

cabergoline/bromocriptine (D agonists)

diabetes inspidius

central>desmopressin nephrogenic> HCZT, indomethacin, amiloride

SIADH

fluid restriction, IV hypertonic saline, conivaptan/tolvaptan, demeclocycline

DKA/HHS

fluids, insulin, K+

pheochromo

alpha-antagonists (phenoxybenzamine)

carcinoid syndrome

octreotide, teltristat

DM1

insulin replacement + low card diet

DM2

oral hypoglycemics, diet interventions, insulin (if refractory from cell exhaustion)

Chrons

corticosteroids, infliximab, azathioprine

ulcerative colitis

5-ASA preparations (mesalamine) 6-mercaptopurine infliximab colectomy

sickle cell anemia

hydroxyurea (inc fetal Hb)

chronic myelogenous leukemia (CML)

BCR-ABL tyrosine kinase inhibitors (imatinib)

acute promyelocytic leukemia (M3)

all-trans retinoic acid, arsenic trioxide

#1 anti-coagulation in pregnancy

low molecular weight heparin

immediate anti-coagulation

heparin

heparin reversal

protamine sulfate

warfarin reversal

vit K (slow response) FFP/prothrombin complex concentrate (fast)

dabigatran reversal

idarucizumab

direct factor Xa inhibitor reversal

andexanet alfa

HER2+ breast cancer

trastuzamab

hemorrhagic cystitis from cyclophasphamide/ifosfamide

mesna

nephrotoxicity from platinum compounds

amifostine

cardiotoxicity from anthracyclines

dexrazoane

myelosuppresion from methotrexate

leucovorin

osteoporosis

Ca/Vit D supplementation (prophylaxis) bisphosphonates, PTH analogs, SERMs, calcitonin, densumab (tx)

osteomalacia/rickets

Vit D supplementation

chronic gout

xanthine oxidase inhibitors (allopurinol, febuxostat) pegloticase probenecid **rasburicase for hyperuricemia in malignancy

acute gout attack

NSAIDs, colchicine, glucocorticoids

buerger disease

smoking cessation

Kawasaki disease

IVIG, aspirin

temporal arteritisi

high dose glucocorticoids

granulomastis w/ polyanggiitis

cyclophosphamide, glucocorticoids

neural tube defect prevention

folaic acid prenatal vitamins

migraine

abortive tx: sumatriptan, NSAIDs prophyalxis: propanolol, topiramate, anti-CGRP antibodies, amitrptyline

disease modifying tx: B-interferon, glatiramer, natalizumab acute flare: IV steroids

tonic-clonic seizures

levetiracetam, phenytonin, valproate, carbamazepine

abscence seizures

ethosuximide

tic doulourex (trigeminal neuralgia)

carbamazepine

maligant hyperthermia (s/p anesthesia)

dantrolene

anorexia

nutrition, psychotx, SSRIs

bulemia nervosa

nutrition, rehabilitation, psychtx, SSRIs

alcohol use disorder

disulfiram, acamprostate, naltrexone, supportive care

ADHD

amphetamines, behavior tx, atomoxetine (non-stimulant)

alcohol withdrawal

long-acting benzos

bipolar disorder

mood stabilizers (lithium, valproic acid, carb) atypical antipsychotics

depression

SSRIs (1st line)

GAD

SSRIs, SNRIs (1st line), buspirone (2nd line)

schizophrenia

atypical antipsychotics

hyperaldosteronism

spironolactone

BPH

a1 antagonists: terazosin, tamsulosin (selective) 5a reductase inhibitors PDE-5 inhibitors TURP

infertility

leuprolide, GnRH (pulsatile), clomiphene

breast cancer in postmenopausal F

aromatase inhibitor (anastrozole)

ER/PR+ breast cancer

tamoxifen

uterine fibroids

leuprolide, GnRH (continuous)

medical abortion

mifepristone

prostate adenocarcinoma

flutamide, GnRH (continuous), degarelix, ketoconazole

erectile dysfunction

sildenafil

pulmonary arterial HTN (idopathic)

sildenafil, bosentan, epoprostenol, iloprost

Rapid Review Relevant Treatments Flashcards

(91 cards)