Recalls 3

Question 1

What are the grading of evidence as per RCOG

Answer 1

A - RCTs, systematic reviews/meta-analyses of RCTs

B - non randomised but well conducted trials

C - case reports

D - expert opinion

Question 2

What is the appendicular artery a branch of

Answer 2

Ileocolic

Question 3

What is teh precursor for serotonin

Answer 3

Tryotophan

Question 4

What is the precursor for dopamine

Answer 4

Tyrosine

Question 5

Define:
Very common
Common
Uncommon
Rare
Very rare

Answer 5

1-1/10
1/10-1/100
1/100-1/1000
1/1000-1/10000
<1/10000

Question 6

What type of molecule are histones

Answer 6

protein

Question 7

Endometrial gland tumour with cartilage

Answer 7

Carcinosarcoma

Question 8

What type of drug is mirabegron

Answer 8

Beta 3 adrenergic receptor agonsit

Question 9

What type of drug is terbutaline

Answer 9

B2 agonist

Question 10

What is a side effect of terbutaline?

MAternal tachy
Fetla tachy
Maternal brady
Fetal brady

Answer 10

Maternal tachy because it is a B2 AGONIST. Think opposite of BB

Question 11

Which inflammatory cells are triggered by silicone implant spillage

Answer 11

Giant cells

Question 12

What is the most common malignant tumour in term or preterm inflants

Answer 12

TERM - neuroblastoma

Pre-term = sacrocyccygeal teratoma (SCT)

Question 13

What does exposure to Diethylstilbestrol (DES) lead to

Answer 13

It is an oestrogen that used to be used to try and prevent miscarriage.

Leads to clear cell cancer of vagina

Question 14

Where is the active form of vitamin D produced

Question 15

Explained Vit D metabolism

Where is it from

Where is it activated

Answer 15

Vit D2 - food
Vit D3 - skin

Changed in liver by 25-hydroxylase

Activated in kidney

Question 16

Which of the cytotoxic drugs causes haemorrhagic cystitis

Answer 16

cyclophosphamide

Question 17

Describe chemo man

Answer 17

Question 18

What type of drug is clomifene

Answer 18

a SERM

Question 19

Which drug causes PND when used postnatally

Answer 19

methyldopa

Question 20

What is the lansfield grouping for streptococci

Answer 20

It groups strep into A,B,C etc based on the antigens made of carbohydrates o their cell wall

Question 21

What is the commonest cause of delay in puberty in males

Answer 21

constitutional delay

Question 22

What type of drug is ulipristal

Answer 22

SPRM

slsective progesterone receptor modulator

Question 23

what is the termination point of the round ligament

Answer 23

The labia majora

Question 24

What does the ductus venosus form

Answer 24

Ligamentum venosum

Question 25

What does the umbilical vein form

Answer 25

ligamentum teres

Question 26

What is the most common organism to colonise the copper iud

Answer 26

actinomyces

Question 27

Which bacteria is depleted in BV

Answer 27

lactobactilus

Question 28

Which is the most common organism causing fetal anaemia? What else does it cause? What is percentage fetal loss?

Answer 28

parvovirus B19

Question 29

What is BMI formula

Answer 29

weight/square root of heing in M

Question 30

Does sheehan syndrome affect anterior or posterior pituitary

Answer 30

Anterior

Question 31

How is lactate converted to glucose

Answer 31

lactic acid cycle aka cori's cycle

Question 32

how to work out abgars

Answer 32

The things that give you a point of 1 are: - blue extremities - grimace rather than a cry - Flexion rather than being active - HR <100 - Resps are gasping and irregular

Question 33

What is the treatment for a MRSA wound infection

Answer 33

Vancomycin

Question 34

Describe the route of estrone creation and estradiol creation

Answer 34

Question 35

What is the most likely electrolyte disturbance from Bendroflumethiazide

Answer 35

hypokalaemia

Question 36

In the developing testis, which cells produce the mullerian inhibiting substance aka AMH

Answer 36

Sertoli cells

Question 37

Which enzyme in red blood cells buffers CO2

Answer 37

Carbonic anhydrase

Question 38

What is definition of maternal mortality and therefore how to figure it out

Answer 38

number of deaths/per births x 100,000 as it is per 100,000

Question 39

What type iof receptor is the progesteron receptor

Answer 39

a nuclear transciption factor receptor. Oestrogen is the same

Question 40

What causes kernicterus

Answer 40

bilirubin too high Sulphonamides e.g. sulfasalazine

Question 41

How does insulin get activated

Answer 41

Removing C peptide C peptide and insulin get sereted 1:1

Question 42

What is the function of mRNA

Answer 42

carrys info from DNA to ribosomes for protein making TRANSLATION It is made by TRANSCRIPTION

Question 43

Which tissues are particularly sensitive to radiation and visa versa

Answer 43

Anything with rapidly dividing cells is sensitive e.g. bone marrow Resistent things: - cerebral neurons - muscle

Question 44

Which electrolyte disturbances associated with SCLC

Answer 44

SIADH - hyponatraemia ALSO hypercalcaemia because of PTH

Question 45

Which type of endometrium does simple hyperplasia most similar to

Answer 45

proliferative

Question 46

Which MHC class is ONLY expressed in placenta

Answer 46

HLA-G Remeber, C,E,G are all expressed A and B are NOT

Question 47

When is the majority of growth hormone secreted

Answer 47

Early sleep

Question 48

Which aprt of the embryo is the origin of the primordial germ cells

Answer 48

The Yolk sac endothelium

Question 49

Where is the greater omentum derived form

Answer 49

The dorsal mesogastrium The lesser omentum comes from the ventral mesentary

Question 50

Which electrolyte disturbance do you get with paralytic ileus

Answer 50

hypokalaemia

Question 51

Where are schiller-duval bodies found

Answer 51

Endodermal sinus tumours

Question 52

Where are signet cells found

Answer 52

krunkenburg tumours

Question 53

Where are walthard cell nests found

Answer 53

brenner tumour

Question 54

How many carbon atoms in: oestrogen THESE 3 ARE PAC-ED: progesterone aldosterone cortisol androgen

Answer 54

18 21 21 21 19

Question 55

What is the max score in PUQE

Answer 55

15

Question 56

what are the second line drugs in hyperemesis

Answer 56

DOM Domperidone ondansetron metoclopramide

Question 57

Where does the carbon base attach on ribose? Where does phosphate attach?

Answer 57

Nitrogenous base attaches to 1 Phosphate base attaches to 5

Question 58

How many people in the UK are Rh-

Answer 58

15%

Question 59

In the horshoe kidney, what structure prevents ascent from pelvis to abdomen

Answer 59

The IMA

Question 60

angle of vagina vs horizontal whislt standing

Answer 60

60 degs Also like the pelvis!

Question 61

which joint resists horizontal rotaiton of the pelvis

Answer 61

The sacroiliac joint

Question 62

2 most common causes of dermatitis in preg

Answer 62

Atopic dermatitis and PUPP OC less common!

Question 63

Most common protozoan causing a zoonotic infection

Answer 63

Toxoplasmosis

Question 64

What teratogenic affect does paroxetine have

Answer 64

Congeital cardiac problems

Question 65

What does vitamin E toxicity do

Answer 65

HAEMORRHAGE

Question 66

What is teh male equivalent of the round ligament

Answer 66

The spermatic cord They are both from the gubernaculum

Question 67

How do you monitor LMWH activity

Answer 67

Anti-Xa activity

Question 68

Timings of congenital conjuctivitis with chlamydia and gonnorrhoea

Answer 68

Chamydia - >5 days Gonnorhoea <5 days

Question 69

How long does NAAT take for chamydia/gonorrhoea

Answer 69

C = 3 weeks G = 2 weeks

Question 70

What type of signalling molecule is prostaglandin

Answer 70

Paracrine - acts locally outside cells

Question 71

Cuarterization of large area of tissue with appearance of smoke is called

Answer 71

Fulguration

Question 72

What is the success rate of COCP to rpevent pregnancy in typical use and perfect use

Answer 72

Typical - 9% Perfect - 0.3%

Question 73

How is isoniazid metabolised in the liver

Answer 73

with acetylation

Question 74

Are the fibres of the internal anal sphincter circular or longitudinal

Answer 74

circular

Question 75

What is the increased cardiac output post delivery as compared to before pregnancy

Answer 75

60-80%

Question 76

What is the risk of ectopic in someone with IUD

Answer 76

1/50

Question 77

What is the rate of miscarriage in couples with baalnced transloacation

Answer 77

25-50%

Question 78

What is the precursor for nitric oxide

Answer 78

L arginine

Question 79

How are amino acids transferred from maternal to fetal circulation? What about glucose?

Answer 79

Amino acids - Active transport Glucose - facilitated diffusion

Question 80

Which clotting factors remain unchanged in pregnancy

Answer 80

2,5,9

Question 81

Calcitonin is secreted by which gland

Answer 81

thyroid - parafollicular cells/chief cells

Question 82

Beta haemolytic strep treatment on vaginal swab

Question 83

Do you give thromboprophylaxis to people with OHSS

Answer 83

Until first trimester ends

Question 84

Why is remifentanyl good in labour

Answer 84

Rapidly metabolised by tissue estrases

Question 85

How to emasure the diagonal conjugate diameter of the pelvis

Answer 85

Lower bit of PS to tip of coccys